Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 8/20 | 0.75 |
| ▸ | TAS1R1 | Q7RTX1 | 8/20 | 0.75 |
| ▸ | TAS1R2 | Q8TE23 | 8/20 | 0.75 |
| ▸ | RAB9A | P51151 | 6/20 | 0.63 |
| ▸ | NPC1 | O15118 | 5/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | NAMPT | P43490 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14817127 | 0.86 | RAB9A (0.82) | TAS1R3TAS1R1TAS1R2RAB9ANPC1 | |
| SCHEMBL705033 | 0.86 | TAS1R3 (1.00) | TAS1R3TAS1R1TAS1R2RAB9ANPC1 | |
| SCHEMBL701894 | 0.83 | TAS1R3 (0.75) | TAS1R3TAS1R1TAS1R2RAB9ANPC1 | |
| SCHEMBL13833355 | 0.83 | TAS1R3 (0.80) | TAS1R3TAS1R1TAS1R2RAB9ANPC1 | |
| SCHEMBL14372234 | 0.82 | RAB9A (0.56) | TAS1R3TAS1R1TAS1R2RAB9ANPC1 | |
| SCHEMBL27102978 | 0.82 | TAS1R3 (0.74) | TAS1R3TAS1R1TAS1R2RAB9ANPC1 | |
| SCHEMBL18079546 | 0.82 | TAS1R3 (0.61) | TAS1R3TAS1R1TAS1R2RAB9ANPC1 | |
| SCHEMBL19860010 | 0.81 | RAB9A (0.71) | RAB9ANPC1LMNATHRBPANK3 | |
| SCHEMBL701754 | 0.81 | TAS1R3 (0.65) | TAS1R3TAS1R1TAS1R2RAB9ANPC1 | |
| SCHEMBL27102975 | 0.81 | TAS1R3 (0.75) | TAS1R3TAS1R1TAS1R2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9890172-B2 | Inhibitors of histone deacetylase | THE BROAD INSTITUTE, INC. (US) | 2018-02-13 | — | — | US | disclosed |