SCHEMBL19860656

SCHEMBL19860656

COCOCC1COCCN1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 1/20 0.32
IRAK4 Q9NWZ3 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29318365 1.00 CNR2 (0.32) CNR2IRAK4
SCHEMBL14635463 0.85
SCHEMBL2911717 0.85
SCHEMBL6133105 0.85
SCHEMBL30230325 0.84 ALOX5 (0.33) CNR2IRAK4
Hydrochloric Acid SCHEMBL6132602 0.83 CNR2 (0.33) CNR2IRAK4
Hydrochloric Acid SCHEMBL3946346 0.83 CNR2 (0.33) CNR2IRAK4
Hydrochloric Acid SCHEMBL3946341 0.83 CNR2 (0.33) CNR2IRAK4
SCHEMBL29318379 0.83 MKNK1 (0.33)
SCHEMBL24937205 0.81 PDK1 (0.36) CNR2IRAK4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3831812-B1 NOVEL 3, 5-DISUBSTITUTED PYRIDINE AND 3, 5-DISUBSTITUTED PYRIDAZINE DERIVATIVES AND PHARMACEUTICAL USE OF SAME MITSUBISHI TANABE PHARMA CORP (JP) 2023-05-10 EP disclosed
US-9890167-B2 Pyrazine compounds for the treatment of infectious diseases HOFFMANN-LA ROCHE INC. (US) 2018-02-13 US disclosed