Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25291699 | 1.00 | PDK1 (0.36) | PDK1CNR2IRAK4 | |
| SCHEMBL12464684 | 1.00 | PDK1 (0.36) | PDK1CNR2IRAK4 | |
| Hydrochloric Acid SCHEMBL6133032 | 0.98 | PDK1 (0.36) | PDK1CNR2IRAK4 | |
| SCHEMBL19860656 | 0.81 | CNR2 (0.32) | CNR2IRAK4 | |
| SCHEMBL10330625 | 0.81 | MKNK1 (0.32) | — | |
| SCHEMBL29318365 | 0.81 | CNR2 (0.32) | CNR2IRAK4 | |
| SCHEMBL30230325 | 0.80 | ALOX5 (0.33) | CNR2IRAK4 | |
| SCHEMBL6133105 | 0.80 | — | — | |
| SCHEMBL2911717 | 0.80 | — | — | |
| SCHEMBL14635463 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230019732-A1 | EGFR INHIBITORS | BLUEPRINT MEDICINES CORPORATION | 2023-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230019732-A1 | EGFR INHIBITORS | EGFR, ERBB2, ERBB3 | PDK1 2654/4885CNR2 4313/4885IRAK4 1794/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.