Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.46 |
| ▸ | CASP2 | P42575 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.41 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.41 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.41 |
| ▸ | RRM1 | P23921 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 2/20 | 0.40 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20076162 | 0.91 | SLC6A5 (0.46) | SLC6A5CASP2EPHX1NAAAGNAI3 | |
| SCHEMBL19861156 | 0.85 | CASP2 (0.42) | SLC6A5CASP2EPHX1NAAARRM1 | |
| SCHEMBL20327677 | 0.82 | RAB9A (0.41) | CASP2EPHX1NAAAFAAH | |
| SCHEMBL19861157 | 0.77 | PAOX (0.45) | SLC6A5 | |
| SCHEMBL20076165 | 0.77 | CASP2 (0.43) | SLC6A5CASP2EPHX1NAAARRM1 | |
| SCHEMBL20327681 | 0.77 | MEN1 (0.54) | EPHX1FAAH | |
| SCHEMBL12335215 | 0.76 | MEN1 (0.42) | SLC6A5CASP2EPHX1NAAAGNAI3 | |
| SCHEMBL23567476 | 0.76 | CASP2 (0.62) | CASP2EPHX1NAAAFAAH | |
| SCHEMBL5878829 | 0.76 | TDP1 (0.52) | — | |
| SCHEMBL5879093 | 0.76 | TDP1 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9890198-B2 | Cyclosporin derivatives and uses thereof | S&T GLOBAL INC. (US) | 2018-02-13 | — | — | US | disclosed |