Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KISS1R | Q969F8 | 1/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.30 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.30 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.30 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.30 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.30 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2736124 | 0.79 | ALDH1A1 (0.33) | PIK3CD | |
| SCHEMBL19861659 | 0.77 | KISS1R (0.33) | KISS1RPIK3CD | |
| SCHEMBL2736120 | 0.76 | CHRNB2 (0.39) | PIK3CD | |
| SCHEMBL2736122 | 0.75 | PIK3CD (0.33) | PIK3CD | |
| SCHEMBL13780659 | 0.75 | PIK3CD (0.33) | PIK3CD | |
| SCHEMBL18532019 | 0.74 | PIK3CD (0.31) | PIK3CD | |
| SCHEMBL19861665 | 0.74 | KISS1R (0.30) | KISS1R | |
| SCHEMBL18531982 | 0.73 | PIK3CD (0.33) | PIK3CD | |
| SCHEMBL18531991 | 0.73 | PIK3CD (0.33) | PIK3CD | |
| SCHEMBL18576496 | 0.73 | PIK3CD (0.37) | PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9891239-B2 | Modulators of pharmacokinetic properties of therapeutics | GILEAD SCIENCES, INC. (US) | 2018-02-13 | — | — | US | disclosed |