Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.30 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.30 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19861705 | 0.86 | CYP2D6 (0.37) | TRPV1 | |
| SCHEMBL2736126 | 0.77 | ALDH1A1 (0.33) | TRPV1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL19861605 | 0.75 | TRPV1 (0.41) | TRPV1UTS2RSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL18531984 | 0.75 | ALDH1A1 (0.31) | TRPV1KMT2AALDH1A1 | |
| SCHEMBL2736129 | 0.74 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL19861658 | 0.71 | TRPV1 (0.38) | TRPV1ALDH1A1 | |
| SCHEMBL13780653 | 0.71 | ACACB (0.37) | TRPV1ALDH1A1 | |
| SCHEMBL18531986 | 0.70 | — | — | |
| SCHEMBL10202726 | 0.66 | ALOX5 (0.31) | ALDH1A1 | |
| SCHEMBL12506705 | 0.65 | PAOX (0.38) | TRPV1UTS2RALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9891239-B2 | Modulators of pharmacokinetic properties of therapeutics | GILEAD SCIENCES, INC. (US) | 2018-02-13 | — | — | US | disclosed |