Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.54 |
| ▸ | NPC1 | O15118 | 5/20 | 0.54 |
| ▸ | RAB9A | P51151 | 5/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16374744 | 0.86 | RAB9A (0.68) | TSHRKDM4ELMNASMN1; SMN2NPC1 | |
| SCHEMBL19861791 | 0.84 | SMN1; SMN2 (0.58) | TSHRKDM4ELMNASMN1; SMN2NPC1 | |
| SCHEMBL1952587 | 0.77 | LMNA (0.55) | TSHRKDM4ELMNASMN1; SMN2NPC1 | |
| SCHEMBL10595749 | 0.76 | LMNA (0.65) | TSHRLMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL19861792 | 0.76 | RAB9A (0.57) | KDM4ELMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL3930649 | 0.75 | MAPT (0.66) | TSHRKDM4ELMNASMN1; SMN2NPC1 | |
| SCHEMBL29666364 | 0.74 | RAB9A (0.70) | TSHRKDM4ELMNASMN1; SMN2NPC1 | |
| SCHEMBL10476873 | 0.72 | RAB9A (0.80) | TSHRKDM4ELMNASMN1; SMN2NPC1 | |
| SCHEMBL698089 | 0.72 | RAB9A (0.60) | TSHRKDM4ELMNASMN1; SMN2NPC1 | |
| SCHEMBL4652669 | 0.71 | LMNA (0.69) | TSHRLMNASMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9890178-B2 | Azabenzimidazoles as respiratory syncytial virus antiviral agents | JANSSEN SCIENCES IRELAND UC (IE) | 2018-02-13 | — | — | US | disclosed |