Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.58 |
| ▸ | NPC1 | O15118 | 5/20 | 0.58 |
| ▸ | RAB9A | P51151 | 5/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | BCHE | P06276 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10595749 | 0.85 | LMNA (0.65) | SMN1; SMN2NPC1RAB9AHPGDL3MBTL1 | |
| SCHEMBL19861792 | 0.84 | RAB9A (0.57) | SMN1; SMN2NPC1RAB9AHPGDL3MBTL1 | |
| SCHEMBL19861778 | 0.84 | TSHR (0.57) | SMN1; SMN2NPC1RAB9AHPGDL3MBTL1 | |
| SCHEMBL16374745 | 0.84 | RAB9A (0.67) | SMN1; SMN2NPC1RAB9AHPGDL3MBTL1 | |
| SCHEMBL21059266 | 0.82 | NPC1 (0.65) | SMN1; SMN2NPC1RAB9AHPGDL3MBTL1 | |
| SCHEMBL21049600 | 0.82 | NPC1 (0.65) | SMN1; SMN2NPC1RAB9AHPGDL3MBTL1 | |
| SCHEMBL13329848 | 0.82 | NPC1 (0.65) | SMN1; SMN2NPC1RAB9AHPGDL3MBTL1 | |
| SCHEMBL12411573 | 0.82 | NPC1 (0.58) | SMN1; SMN2NPC1RAB9AHPGDL3MBTL1 | |
| SCHEMBL21059157 | 0.82 | RAB9A (0.73) | SMN1; SMN2NPC1RAB9AHPGDL3MBTL1 | |
| SCHEMBL2092836 | 0.81 | L3MBTL1 (0.56) | SMN1; SMN2NPC1RAB9AHPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9890178-B2 | Azabenzimidazoles as respiratory syncytial virus antiviral agents | JANSSEN SCIENCES IRELAND UC (IE) | 2018-02-13 | — | — | US | disclosed |