SCHEMBL19861959

SCHEMBL19861959

Cc1cc(O)cc(C)c1CC(N)C(=O)OCc1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
OPRK1 P41145 11/20 0.55
OPRM1 P35372 2/20 0.53
OPRD1 P41143 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21096420 1.00 OPRK1 (0.55) OPRK1OPRM1OPRD1
SCHEMBL21097053 0.88 OPRK1 (0.44) OPRK1OPRM1OPRD1
SCHEMBL29313041 0.84 ALDH1A1 (0.46) OPRK1OPRM1OPRD1
SCHEMBL19861960 0.84 ALDH1A1 (0.46) OPRK1OPRM1OPRD1
SCHEMBL30162392 0.82 CYP3A4 (0.46) OPRK1OPRM1OPRD1
SCHEMBL18072580 0.81 TACR1 (0.49) OPRK1OPRM1OPRD1
SCHEMBL27406548 0.81 SLC7A5 (0.50)
SCHEMBL14617681 0.81 SLC7A5 (0.48)
SCHEMBL25021582 0.81 OPRK1 (0.41) OPRK1OPRM1OPRD1
SCHEMBL27406568 0.81 ALDH1A1 (0.49)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3800192-A1 PROCESSES FOR PREPARING PHARMACEUTICALLY RELEVANT PEPTIDES Stealth Biotherapeutics Corp (MC) 2021-04-07 EP disclosed
EP-3265109-B1 PROCESSES FOR PREPARING PHARMACEUTICALLY RELEVANT PEPTIDES STEALTH BIOTHERAPEUTICS CORP (MC) 2020-10-21 EP disclosed
US-10633415-B2 Processes for preparing pharmaceutically relevant peptides STEALTH BIOTHERAPEUTICS CORP (MC) 2020-04-28 US disclosed
US-20180044378-A1 PROCESSES FOR PREPARING PHARMACEUTICALLY RELEVANT PEPTIDES STEALTH BIOTHERAPEUTICS INC. 2018-02-15 US disclosed
US-20180044378-A1 PROCESSES FOR PREPARING PHARMACEUTICALLY RELEVANT PEPTIDES STEALTH BIOTHERAPEUTICS INC. 2018-02-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180044378-A1 PROCESSES FOR PREPARING PHARMACEUTICALLY RELEVANT PEPTIDES ADM2, VIP, PEPD OPRK1 2236/4885OPRM1 1092/4885OPRD1 1708/4885
US-10633415-B2 Processes for preparing pharmaceutically relevant peptides ADM2, VIP, PEPD OPRK1 2236/4885OPRM1 1092/4885OPRD1 1708/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.