Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TACR1 | P25103 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29313041 | 1.00 | ALDH1A1 (0.46) | ALDH1A1OPRK1OPRD1OPRM1NPC1 | |
| SCHEMBL26604643 | 0.88 | ALDH1A1 (0.43) | ALDH1A1NPC1RAB9ALMNATACR1 | |
| SCHEMBL21096420 | 0.84 | OPRK1 (0.55) | OPRK1OPRD1OPRM1 | |
| SCHEMBL19861959 | 0.84 | OPRK1 (0.55) | OPRK1OPRD1OPRM1 | |
| SCHEMBL18072580 | 0.82 | TACR1 (0.49) | ALDH1A1OPRK1OPRD1OPRM1NPC1 | |
| SCHEMBL12764099 | 0.81 | ALDH1A1 (0.58) | ALDH1A1NPC1RAB9ATACR1 | |
| SCHEMBL265561 | 0.81 | ALDH1A1 (0.58) | ALDH1A1NPC1RAB9ATACR1 | |
| SCHEMBL265176 | 0.81 | ALDH1A1 (0.58) | ALDH1A1NPC1RAB9ATACR1 | |
| SCHEMBL8268036 | 0.79 | LMNA (0.54) | ALDH1A1LMNA | |
| SCHEMBL16080197 | 0.79 | LMNA (0.54) | ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11795196-B2 | Mitochondria-targeting peptides | STEALTH BIOTHERAPEUTICS INC. (US) | 2023-10-24 | — | — | US | disclosed |
| US-20180044378-A1 | PROCESSES FOR PREPARING PHARMACEUTICALLY RELEVANT PEPTIDES | STEALTH BIOTHERAPEUTICS INC. | 2018-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180044378-A1 | PROCESSES FOR PREPARING PHARMACEUTICALLY RELEVANT PEPTIDES | ADM2, VIP, PEPD | ALDH1A1 4638/4885OPRK1 2236/4885OPRD1 1708/4885 |
| US-11795196-B2 | Mitochondria-targeting peptides | HSPE1, TFAM, TNNI3 | ALDH1A1 3737/4885OPRK1 3460/4885OPRD1 3815/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.