SCHEMBL19862245

SCHEMBL19862245

C1=Cc2ccc(-c3nc(-c4ccccc4)nc(-c4cccc(-c5ccccc5)c4)n3)cc2C2(c3ccccc31)c1ccccc1-c1c2ccc2oc3ccccc3c12

nearest known ligand 0.31

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PLA2G2A P14555 3/20 0.31
PLA2G4A P47712 3/20 0.31
PLA2G10 O15496 1/20 0.31
PIM1 P11309 1/20 0.30
CSNK2A2 P19784 1/20 0.30
CSNK2B P67870 1/20 0.30
PIM3 Q86V86 1/20 0.30
PIM2 Q9P1W9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19862241 0.97 WEE1 (0.30)
SCHEMBL19862126 0.96 WEE1 (0.31)
SCHEMBL19862234 0.92 NR1I3 (0.34) PIM1CSNK2A2CSNK2B
SCHEMBL19862238 0.92 KMT2A (0.33)
SCHEMBL19862249 0.92 KMT2A (0.32)
SCHEMBL19862240 0.90 PDK2 (0.35) PIM1PIM2
SCHEMBL19862117 0.89 ALOX5 (0.33) PIM1CSNK2A2CSNK2BPIM3PIM2
SCHEMBL20224484 0.89 PLA2G2A (0.33) PLA2G2APLA2G4APLA2G10PIM1CSNK2A2
SCHEMBL19131547 0.88 PLA2G2A (0.34) PLA2G2APLA2G4APLA2G10
SCHEMBL19862254 0.88 MEN1 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10454039-B2 Compound and organic electronic device using the same SHANGHAI NICHEM FINE CHEMICAL CO., LTD. (CN) 2019-10-22 US disclosed
US-20180047918-A1 COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME NICHEM FINE TECHNOLOGY CO., LTD. (TW) 2018-02-15 US disclosed
US-20180047918-A1 COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME NICHEM FINE TECHNOLOGY CO., LTD. (TW) 2018-02-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180047918-A1 COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME ORC3, AOX1, RCOR3 PLA2G2A 4552/4885PLA2G4A 4501/4885PLA2G10 4657/4885
US-10454039-B2 Compound and organic electronic device using the same ORC3, AOX1, RCOR3 PLA2G2A 4552/4885PLA2G4A 4501/4885PLA2G10 4657/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.