Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | AKT1 | P31749 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | CTSL | P07711 | 2/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KLK7 | P49862 | 1/20 | 0.41 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1728479 | 0.83 | SYK (0.53) | SYKPPARAMEN1KMT2ACA12 | |
| SCHEMBL7216943 | 0.81 | SYK (0.54) | SYKPPARAMEN1KMT2ACA12 | |
| SCHEMBL7485771 | 0.81 | SYK (0.48) | SYKPPARAMEN1KMT2ACA12 | |
| SCHEMBL27524219 | 0.80 | SYK (0.50) | SYKPPARAMEN1KMT2ACA12 | |
| SCHEMBL7434905 | 0.80 | SYK (0.50) | SYKPPARAMEN1KMT2ACA12 | |
| SCHEMBL8312542 | 0.80 | SYK (0.50) | SYKPPARAMEN1KMT2ACA12 | |
| SCHEMBL7432755 | 0.80 | SYK (0.53) | SYKPPARAMEN1KMT2ACA12 | |
| SCHEMBL29291807 | 0.80 | SYK (0.53) | SYKPPARAMEN1KMT2ACA12 | |
| SCHEMBL21239559 | 0.80 | SYK (0.53) | SYKPPARAMEN1KMT2ACA12 | |
| SCHEMBL22648245 | 0.79 | SYK (0.49) | SYKPPARAMEN1KMT2ACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180044375-A1 | DEUTERATED EMRICASAN | CONCERT PHARMACEUTICALS INC (US) | 2018-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180044375-A1 | DEUTERATED EMRICASAN | TMPRSS15, HPN, CASP3 | SYK 3203/4885PPARA 911/4885MEN1 2150/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.