Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 3/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | AKT1 | P31749 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8931457 | 0.87 | SYK (0.44) | SYKPPARAMEN1KMT2ACTSS | |
| SCHEMBL1728479 | 0.82 | SYK (0.53) | SYKPPARAMEN1KMT2ACTSS | |
| SCHEMBL10382701 | 0.81 | SYK (0.43) | SYKPPARAMEN1KMT2ACA12 | |
| SCHEMBL560683 | 0.81 | ALDH1A1 (0.49) | SYKPPARAMEN1KMT2ACTSS | |
| SCHEMBL560684 | 0.81 | ALDH1A1 (0.49) | SYKPPARAMEN1KMT2ACTSS | |
| SCHEMBL19862502 | 0.81 | SYK (0.49) | SYKPPARAMEN1KMT2ACTSS | |
| SCHEMBL7216943 | 0.80 | SYK (0.54) | SYKPPARAMEN1KMT2ACTSS | |
| SCHEMBL28168067 | 0.79 | ALDH1A1 (0.51) | SYKPPARACTSSCA12CA1 | |
| SCHEMBL21239559 | 0.79 | SYK (0.53) | SYKPPARAMEN1KMT2ACTSS | |
| SCHEMBL8312542 | 0.79 | SYK (0.50) | SYKPPARAMEN1KMT2ACTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996033982-A1 | PIPERAZINONES USEFUL AS INHIBITORS OF PLATELET AGGREGATION | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-10-31 | — | — | WO | disclosed |