SCHEMBL19862617

SCHEMBL19862617

CNC(=O)N[C@]1(C)CCC[C@@]2(C)C3CC[C@@]4(C)C[C@]3(CCC21)CC4=O

nearest known ligand 0.63

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
F10 P00742 8/20 0.63
PTPN1 P18031 4/20 0.63
PTPN2 P17706 3/20 0.63
CDC25B P30305 3/20 0.63
L3MBTL1 Q9Y468 1/20 0.53
BCHE P06276 4/20 0.51
ACHE P22303 4/20 0.48
HSD11B1 P28845 2/20 0.46
ATM Q13315 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19862616 0.89 HSD11B1 (0.51) F10PTPN1PTPN2CDC25BL3MBTL1
SCHEMBL2030356 0.78 F10 (0.70) F10PTPN1PTPN2CDC25BL3MBTL1
Isosteviol SCHEMBL14925190 0.77 F10 (1.00) F10PTPN1PTPN2CDC25BL3MBTL1
Isosteviol SCHEMBL22922207 0.77 F10 (1.00) F10PTPN1PTPN2CDC25BL3MBTL1
Isosteviol SCHEMBL439433 0.77 F10 (1.00) F10PTPN1PTPN2CDC25BL3MBTL1
Isosteviol SCHEMBL2987296 0.77 F10 (1.00) F10PTPN1PTPN2CDC25BL3MBTL1
Isosteviol SCHEMBL13401807 0.77 F10 (1.00) F10PTPN1PTPN2CDC25BL3MBTL1
Isosteviol SCHEMBL2025230 0.77 F10 (1.00) F10PTPN1PTPN2CDC25BL3MBTL1
Isosteviol SCHEMBL3489810 0.77 F10 (1.00) F10PTPN1PTPN2CDC25BL3MBTL1
Isosteviol SCHEMBL26990273 0.77 F10 (1.00) F10PTPN1PTPN2CDC25BL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180042874-A1 METHOD FOR TREATING OSTEOPOROSIS CHINA MEDICAL UNIVERSITY (TW) 2018-02-15 US disclosed
US-20180042874-A1 METHOD FOR TREATING OSTEOPOROSIS CHINA MEDICAL UNIVERSITY (TW) 2018-02-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180042874-A1 METHOD FOR TREATING OSTEOPOROSIS SOST, PTH1R, CYP24A1 F10 2201/4885PTPN1 2539/4885PTPN2 2485/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.