Isosteviol

Isosteviol

SCHEMBL439433

CC12CCC3C(CCC4C(C)(C(=O)O)CCCC34C)(CC1=O)C2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
F10 P00742 9/20 1.00
PTPN1 P18031 5/20 1.00
PTPN2 P17706 3/20 1.00
CDC25B P30305 3/20 1.00
BCHE P06276 4/20 0.64
L3MBTL1 Q9Y468 1/20 0.64
ACHE P22303 4/20 0.59
HSD11B1 P28845 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Isosteviol SCHEMBL22922207 1.00 F10 (1.00) F10PTPN1PTPN2CDC25BBCHE
Isosteviol SCHEMBL3489810 1.00 F10 (1.00) F10PTPN1PTPN2CDC25BBCHE
Isosteviol SCHEMBL13401648 1.00 F10 (1.00) F10PTPN1PTPN2CDC25BBCHE
Isosteviol SCHEMBL2987296 1.00 F10 (1.00) F10PTPN1PTPN2CDC25BBCHE
Isosteviol SCHEMBL14925190 1.00 F10 (1.00) F10PTPN1PTPN2CDC25BBCHE
Isosteviol SCHEMBL2025230 1.00 F10 (1.00) F10PTPN1PTPN2CDC25BBCHE
Isosteviol SCHEMBL26990273 1.00 F10 (1.00) F10PTPN1PTPN2CDC25BBCHE
Isosteviol SCHEMBL13401807 1.00 F10 (1.00) F10PTPN1PTPN2CDC25BBCHE
SCHEMBL17066125 0.87 F10 (0.77) F10PTPN1PTPN2CDC25BBCHE
SCHEMBL13242208 0.87 F10 (0.77) F10PTPN1PTPN2CDC25BBCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2214681-B1 NOVEL NUTRACEUTICAL COMPOSITIONS CONTAINING STEVIOL AND USES THEREOF DSM IP ASSETS BV (NL) 2021-10-20 EP disclosed
EP-2595598-B1 TOPICAL USE OF STEVIOL OR ISOSTEVIOL IN HAIR CARE DSM IP ASSETS BV (NL) 2017-12-06 EP disclosed
EP-2595598-B1 TOPICAL USE OF STEVIOL OR ISOSTEVIOL IN HAIR CARE DSM IP ASSETS BV (NL) 2017-12-06 EP disclosed
CN-103002866-B Flos Chrysanthemi or the derivant topical use in hair-care DSM IP ASSETS B.V. (NL) 2016-03-16 CN disclosed
US-20140044656-A1 NOVEL USE DSM IP ASSETS B.V. (NL) 2014-02-13 US disclosed
CN-101883568-B Nutraceutical compositions containing stevia extract or stevia extract constituents and uses thereof DSM IP ASSETS BV 2013-12-18 CN disclosed
EP-2595598-A2 TOPICAL USE OF STEVIOL OR DERIVATIVES IN HAIR CARE DSM IP Assets B.V. (NL) 2013-05-29 EP disclosed
US-20130115182-A1 TOPICAL USE OF STEVIOL OR DERIVATIVES IN HAIR CARE DSM NUTRITIONAL PRODUCTS LTD. (NL) 2013-05-09 US disclosed
US-20130115182-A1 TOPICAL USE OF STEVIOL OR DERIVATIVES IN HAIR CARE DSM NUTRITIONAL PRODUCTS LTD. (NL) 2013-05-09 US disclosed
US-20130115182-A1 TOPICAL USE OF STEVIOL OR DERIVATIVES IN HAIR CARE DSM NUTRITIONAL PRODUCTS LTD. (NL) 2013-05-09 US disclosed
US-20110251381-A1 METHOD TO MAKE STEVIOL GLYCOSIDE ISOMERS PEPSICO, INC. (US) 2011-10-13 US disclosed
US-7964232-B2 Steviol glycoside isomers PEPSICO, INC. (US) 2011-06-21 US disclosed
US-7964232-B2 Steviol glycoside isomers PEPSICO, INC. (US) 2011-06-21 US disclosed
US-20110038957-A1 NOVEL NUTRACEUTICAL COMPOSITIONS CONTAINING STEVIA EXTRACT OR STEVIA EXTRACT CONSTITUENTS AND USES THEREOF DSM IP ASSETS B.V. (NL) 2011-02-17 US disclosed
CN-101883568-A Novel nutraceutical compositions containing stevia extract or stevia extract constituents and uses thereof DSM IP ASSETS BV 2010-11-10 CN disclosed
EP-2214681-A1 NOVEL NUTRACEUTICAL COMPOSITIONS CONTAINING STEVIA EXTRACT OR STEVIA EXTRACT CONSTITUENTS AND USES THEREOF DSM IP Assets B.V. (NL) 2010-08-11 EP disclosed
WO-2009071277-A1 NOVEL NUTRACEUTICAL COMPOSITIONS CONTAINING STEVIA EXTRACT OR STEVIA EXTRACT CONSTITUENTS AND USES THEREOF DSM IP ASSETS B.V. (NL) 2009-06-11 WO disclosed
WO-2009038978-A2 STEVIOL GLYCOSIDE ISOMERS PEPSICO, INC. (US) 2009-03-26 WO disclosed
US-20090074935-A1 STEVIOL GLYCOSIDE ISOMERS PEPSICO, INC. (US) 2009-03-19 US disclosed
US-20090074935-A1 STEVIOL GLYCOSIDE ISOMERS PEPSICO, INC. (US) 2009-03-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110251381-A1 METHOD TO MAKE STEVIOL GLYCOSIDE ISOMERS DEGS1, TAS1R2, TAS2R1 F10 1710/4885PTPN1 2056/4885PTPN2 2220/4885
US-20130115182-A1 TOPICAL USE OF STEVIOL OR DERIVATIVES IN HAIR CARE POLR1C, CCND3, DRD3 F10 3541/4885PTPN1 4309/4885PTPN2 4108/4885
US-20110038957-A1 NOVEL NUTRACEUTICAL COMPOSITIONS CONTAINING STEVIA EXTRACT OR STEVIA EXTRACT CONSTITUENTS AND USES THEREOF SYNGR2, FABP7, PSD F10 2833/4885PTPN1 4139/4885PTPN2 3704/4885
US-20140044656-A1 NOVEL USE TYR, TPST2, MC1R F10 1432/4885PTPN1 3211/4885PTPN2 2029/4885
US-20090074935-A1 STEVIOL GLYCOSIDE ISOMERS DEGS1, TAS1R2, TAS2R1 F10 1747/4885PTPN1 2095/4885PTPN2 2113/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.