Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
| ▸ | ALPG | P10696 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18590478 | 1.00 | NPSR1 (0.40) | NPSR1MAPTATMPOLBKMT2A | |
| SCHEMBL18590479 | 0.98 | POLB (0.41) | NPSR1MAPTATMPOLBKMT2A | |
| SCHEMBL19862621 | 0.98 | POLB (0.41) | NPSR1MAPTATMPOLBKMT2A | |
| SCHEMBL19862622 | 0.77 | NPSR1 (0.49) | NPSR1MAPTATMKMT2ASMN1; SMN2 | |
| SCHEMBL18590477 | 0.77 | NPSR1 (0.49) | NPSR1MAPTATMKMT2ASMN1; SMN2 | |
| SCHEMBL19862623 | 0.70 | SMN1; SMN2 (0.40) | NPSR1MAPTATMPOLBKMT2A | |
| SCHEMBL18590511 | 0.70 | SMN1; SMN2 (0.40) | NPSR1MAPTATMPOLBKMT2A | |
| SCHEMBL18590513 | 0.69 | POLB (0.42) | POLBKMT2ASMN1; SMN2AKR1B1THRB | |
| SCHEMBL19862626 | 0.69 | POLB (0.42) | POLBKMT2ASMN1; SMN2AKR1B1THRB | |
| SCHEMBL12911750 | 0.68 | POLB (0.41) | NPSR1MAPTATMPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10029983-B2 | Urea derivative or pharmacologically acceptable salt thereof | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2018-07-24 | — | — | US | disclosed |
| US-20180044290-A1 | UREA DERIVATIVE OR PHARMACOLOGICALLY ACCEPTABLE SALT THEREOF | KYORIN SEIYAKU KK (JP) | 2018-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10029983-B2 | Urea derivative or pharmacologically acceptable salt thereof | FPR1, FPR2, FPR3 | NPSR1 34/4885MAPT 3087/4885ATM 4814/4885 |
| US-20180044290-A1 | UREA DERIVATIVE OR PHARMACOLOGICALLY ACCEPTABLE SALT THEREOF | FPR1, FPR2, FPR3 | NPSR1 34/4885MAPT 3087/4885ATM 4814/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.