Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB2 | Q96IY4 | 8/20 | 0.48 |
| ▸ | CPA1 | P15085 | 1/20 | 0.43 |
| ▸ | CPB1 | P15086 | 2/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 7/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 6/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | CACNA1H | O95180 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7743898 | 0.86 | CPB2 (0.62) | CPB2CPA1CPB1DAO | |
| Lithium Ion SCHEMBL7743896 | 0.85 | CPB2 (0.50) | CPB2CPA1CPB1CYP11B2CYP11B1 | |
| SCHEMBL7086614 | 0.82 | CPA1 (0.51) | CPB2CPA1CPB1CYP11B2CYP11B1 | |
| SCHEMBL7704747 | 0.80 | CACNA1H (0.40) | CPB2CYP11B2CYP11B1DAOCACNA1H | |
| SCHEMBL25211567 | 0.77 | CACNA1H (0.43) | DAOCACNA1H | |
| SCHEMBL19862704 | 0.76 | ESR1 (0.49) | CYP11B2CYP11B1CACNA1H | |
| SCHEMBL8865811 | 0.76 | CPA1 (0.57) | CPB2CPA1CPB1 | |
| SCHEMBL8764039 | 0.76 | CPA1 (0.72) | CPB2CPA1CPB1 | |
| SCHEMBL7749570 | 0.73 | CPA1 (0.50) | CPB2CPA1CPB1 | |
| SCHEMBL7704752 | 0.70 | DAO (0.40) | CYP11B2CYP11B1DAOCACNA1H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091736-A4 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO INC (US) | 2001-10-24 | — | — | EP | disclosed |
| EP-1091736-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | Merck & Co., Inc. (US) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001382-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 2000-01-13 | — | — | WO | disclosed |