Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | TSHR | P16473 | 5/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6540127 | 0.93 | ALDH1A1 (0.43) | LTA4HALDH1A1TSHRTDP1L3MBTL1 | |
| SCHEMBL18207524 | 0.89 | KDM4E (0.33) | ALDH1A1L3MBTL1 | |
| SCHEMBL10713027 | 0.84 | LTA4H (0.41) | LTA4HCYP1A2CYP2C19CYP2C9ALDH1A1 | |
| SCHEMBL7760662 | 0.84 | ALDH1A1 (0.42) | LTA4HCYP1A2CYP2C19CYP2C9ALDH1A1 | |
| SCHEMBL2873600 | 0.81 | DPP4 (0.31) | TSHR | |
| SCHEMBL160796 | 0.81 | DPP4 (0.31) | TSHR | |
| SCHEMBL7634483 | 0.80 | TSHR (0.40) | TSHR | |
| SCHEMBL1985558 | 0.80 | TSHR (0.34) | TSHR | |
| SCHEMBL27603326 | 0.79 | DPP4 (0.30) | — | |
| SCHEMBL8740877 | 0.79 | TDP1 (0.32) | TDP1L3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102781937-B | As two (difluoromethyl) pyrazoles of sterilant | BAYER CROPSCIENCE AG (DE) | 2015-09-30 | — | — | CN | claimed |
| EP-2516426-B1 | BIS(DIFLUORMETHYL)PYRAZOLES USED AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2015-09-16 | — | — | EP | claimed |
| US-20140057945-A1 | Bis(difluoromethyl)pyrazoles as Fungicides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-02-27 | — | — | US | claimed |
| US-8524743-B2 | Bis(difluoromethyl)pyrazoles as fungicides | BAYER CROPSCIENCE AG (DE) | 2013-09-03 | — | — | US | claimed |
| CN-102781937-A | Bis(difluormethyl)pyrazoles used as fungicides | BAYER CROPSCIENCE AG | 2012-11-14 | — | — | CN | claimed |
| EP-2516426-A1 | BIS(DIFLUORMETHYL)PYRAZOLES USED AS FUNGICIDES | Bayer CropScience AG (DE) | 2012-10-31 | — | — | EP | claimed |
| US-20110224257-A1 | Bis(difluoromethyl)pyrazoles as Fungicides | BAYER CROPSCIENCE AG (DE) | 2011-09-15 | — | — | US | claimed |
| WO-2011076699-A1 | BIS(DIFLUORMETHYL)PYRAZOLES USED AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2011-06-30 | — | — | WO | claimed |
| US-9751871-B2 | Bis(difluoromethyl)pyrazoles as fungicides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2017-09-05 | — | — | US | disclosed |
| US-20160214970-A1 | Bis(difluoromethyl)pyrazoles as Fungicides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-07-28 | — | — | US | disclosed |
| US-9247748-B2 | Bis(difluoromethyl)pyrazoles as fungicides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-02-02 | — | — | US | disclosed |
| US-9167821-B2 | Bis(difluoromethyl)pyrazoles as fungicides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-10-27 | — | — | US | disclosed |
| CN-102781937-B | As two (difluoromethyl) pyrazoles of sterilant | BAYER CROPSCIENCE AG (DE) | 2015-09-30 | — | — | CN | disclosed |
| EP-2516426-B1 | BIS(DIFLUORMETHYL)PYRAZOLES USED AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2015-09-16 | — | — | EP | disclosed |
| CN-102781937-A | Bis(difluormethyl)pyrazoles used as fungicides | BAYER CROPSCIENCE AG | 2012-11-14 | — | — | CN | disclosed |
| EP-2516426-A1 | BIS(DIFLUORMETHYL)PYRAZOLES USED AS FUNGICIDES | Bayer CropScience AG (DE) | 2012-10-31 | — | — | EP | disclosed |
| US-20110224257-A1 | Bis(difluoromethyl)pyrazoles as Fungicides | BAYER CROPSCIENCE AG (DE) | 2011-09-15 | — | — | US | disclosed |
| WO-2011076699-A1 | BIS(DIFLUORMETHYL)PYRAZOLES USED AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2011-06-30 | — | — | WO | disclosed |
| EP-2176251-A2 | 5-PYRIDINONE SUBSTITUTED INDAZOLES | Albany Molecular Research, Inc. (US) | 2010-04-21 | — | — | EP | disclosed |
| WO-2009015037-A2 | 5-PYRIDINONE SUBSTITUTED INDAZOLES | ALBANY MOLECULAR RESEARCH, INC. (US) | 2009-01-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160214970-A1 | Bis(difluoromethyl)pyrazoles as Fungicides | CYP1A1, CYP4X1, CYP2F1 | LTA4H 4340/4885CYP1A2 20/4885CYP2C19 80/4885 |
| US-20110224257-A1 | Bis(difluoromethyl)pyrazoles as Fungicides | CYP1A1, CYP4X1, CYP2F1 | LTA4H 4340/4885CYP1A2 20/4885CYP2C19 80/4885 |
| US-20140057945-A1 | Bis(difluoromethyl)pyrazoles as Fungicides | CYP1A1, CYP4X1, CYP2F1 | LTA4H 4340/4885CYP1A2 20/4885CYP2C19 80/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.