Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | APAF1 | O14727 | 2/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1986314 | 0.93 | LTA4H (0.38) | ALDH1A1APAF1RAD52NPSR1TSHR | |
| SCHEMBL18207524 | 0.86 | KDM4E (0.33) | ALDH1A1LMNANPC1MEN1KMT2A | |
| SCHEMBL16058456 | 0.85 | ALDH1A1 (0.42) | ALDH1A1APAF1RAD52NPSR1TSHR | |
| SCHEMBL16055969 | 0.85 | ALDH1A1 (0.42) | ALDH1A1APAF1RAD52NPSR1TSHR | |
| SCHEMBL8740877 | 0.83 | TDP1 (0.32) | SMN1; SMN2MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL27168725 | 0.79 | KCNH2 (0.39) | — | |
| SCHEMBL2873600 | 0.78 | DPP4 (0.31) | TSHRKDM4EPOLB | |
| SCHEMBL160796 | 0.78 | DPP4 (0.31) | TSHRKDM4EPOLB | |
| SCHEMBL10713027 | 0.78 | LTA4H (0.41) | ALDH1A1APAF1RAD52NPSR1TSHR | |
| SCHEMBL7760662 | 0.78 | ALDH1A1 (0.42) | ALDH1A1APAF1RAD52NPSR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040082757-A1 | Echinocandin derivatives, pharmaceutical compositions containing same and use thereof as drugs | ASTELLAS PHARMA INC. (JP) | 2004-04-29 | — | — | US | disclosed |
| EP-1366065-A1 | ECHINOCANDIN DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME AND USE THEREOF AS DRUGS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-12-03 | — | — | EP | disclosed |
| WO-2002068456-A1 | ECHINOCANDIN DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME AND USE THEREOF AS DRUGS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-09-06 | — | — | WO | disclosed |
| US-6232290-B1 | FUNGICIDES AGAINST PNEUMOCYSTIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-15 | — | — | US | disclosed |
| EP-1053247-A1 | ANTIFUNGAL CYCLOHEXAPEPTIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-22 | — | — | EP | disclosed |
| WO-1999040108-A1 | NEW COMPOUND | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-08-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040082757-A1 | Echinocandin derivatives, pharmaceutical compositions containing same and use thereof as drugs | MAN2B1, MAN2A1, ALG1 | ALDH1A1 1715/4885APAF1 857/4885RAD52 4626/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.