SCHEMBL19863252

SCHEMBL19863252

CC(C(=O)c1ccc(-c2ccccc2)cc1)C(F)(F)F

nearest known ligand 0.53

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 8/20 0.53
LMNA P02545 4/20 0.53
HTT P42858 4/20 0.53
ALDH1A1 P00352 3/20 0.53
MAPT P10636 3/20 0.50
PDCD1 Q15116 1/20 0.50
CD274 Q9NZQ7 1/20 0.50
KDM4E B2RXH2 1/20 0.49
L3MBTL1 Q9Y468 2/20 0.46
PTGS2 P35354 1/20 0.46
POLB P06746 1/20 0.44
NPC1 O15118 3/20 0.44
RAB9A P51151 3/20 0.44
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
HPGD P15428 1/20 0.43
CTDSP1 Q9GZU7 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2201172 0.89 CES1 (0.48) SMN1; SMN2LMNAHTTALDH1A1MAPT
Hydrochloric Acid SCHEMBL5819903 0.87 CES1 (0.47) SMN1; SMN2LMNAHTTALDH1A1MAPT
SCHEMBL19863243 0.85 KMO (0.51) LMNAMAPT
SCHEMBL28020023 0.81 SMN1; SMN2 (0.48) SMN1; SMN2LMNAHTTALDH1A1MAPT
SCHEMBL19863238 0.79 CA2 (0.48) SMN1; SMN2LMNAHTTALDH1A1MAPT
SCHEMBL2625198 0.79 SMN1; SMN2 (0.61) SMN1; SMN2LMNAHTTALDH1A1MAPT
SCHEMBL28729503 0.79 SMN1; SMN2 (0.46) SMN1; SMN2LMNAHTTALDH1A1MAPT
SCHEMBL19866845 0.78 GSK3B (0.61) NPC1RAB9AMEN1KMT2AHPGD
SCHEMBL19863239 0.76 KDM4E (0.52) SMN1; SMN2ALDH1A1MAPTKDM4ENPC1
SCHEMBL8995348 0.76 SMN1; SMN2 (0.57) SMN1; SMN2LMNAHTTALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9983475-B2 Fluorinated sulfonate esters of aryl ketones for non-ionic photo-acid generators INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2018-05-29 US disclosed
US-9983475-B2 Fluorinated sulfonate esters of aryl ketones for non-ionic photo-acid generators INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2018-05-29 US disclosed
US-20180046077-A1 FLUORINATED SULFONATE ESTERS OF ARYL KETONES FOR NON-IONIC PHOTO-ACID GENERATORS INTERNATIONAL BUSINESS MACHINES CORPORATION 2018-02-15 US disclosed
US-20180046077-A1 FLUORINATED SULFONATE ESTERS OF ARYL KETONES FOR NON-IONIC PHOTO-ACID GENERATORS INTERNATIONAL BUSINESS MACHINES CORPORATION 2018-02-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180046077-A1 FLUORINATED SULFONATE ESTERS OF ARYL KETONES FOR NON-IONIC PHOTO-ACID GENERATORS PFAS, PLG, PPARG SMN1; SMN2 3911/4885LMNA 381/4885HTT 1150/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.