⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7723019 | 0.86 | LMNA (0.33) | — | |
| SCHEMBL10472957 | 0.78 | — | — | |
| SCHEMBL21643624 | 0.78 | ALOX5 (0.37) | — | |
| SCHEMBL28395981 | 0.77 | — | — | |
| SCHEMBL22692534 | 0.77 | LMNA (0.31) | — | |
| SCHEMBL6305828 | 0.77 | LMNA (0.31) | — | |
| SCHEMBL7037590 | 0.77 | LMNA (0.31) | — | |
| SCHEMBL10903154 | 0.77 | — | — | |
| SCHEMBL10959204 | 0.77 | TDP1 (0.42) | — | |
| SCHEMBL417414 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180043313-A1 | FLUOROPOLYMERS AND MEMBRANES COMPRISING FLUOROPOLYMERS (I) | PALL CORPORATION (US) | 2018-02-15 | — | — | US | disclosed |