SCHEMBL19863549

SCHEMBL19863549

C=Cc1ccc(COCCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)cc1

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PTPN2 P17706 1/20 0.33
PTPN1 P18031 1/20 0.33
PTPN6 P29350 1/20 0.33
CA1 P00915 3/20 0.32
CA2 P00918 3/20 0.32
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8623184 1.00 PTPN2 (0.33) PTPN2PTPN1PTPN6CA1CA2
SCHEMBL7790930 0.99 PTPN2 (0.33) PTPN2PTPN1PTPN6CA1CA2
SCHEMBL1081718 0.83 PTPN2 (0.36) PTPN2PTPN1PTPN6CA1CA2
SCHEMBL7795363 0.82 ALDH1A1 (0.38) PTPN2PTPN1PTPN6ALDH1A1
SCHEMBL25513624 0.80 ALDH1A1 (0.37) CA1CA2ALDH1A1
SCHEMBL25513621 0.80 ALDH1A1 (0.37) CA1CA2ALDH1A1
SCHEMBL12539840 0.79 CHRNA7 (0.44) ALDH1A1
SCHEMBL7790933 0.79 ALDH1A1 (0.37) CA1CA2ALDH1A1
SCHEMBL25513628 0.79 ALDH1A1 (0.38) CA1CA2ALDH1A1
SCHEMBL14369391 0.78 CHRNA7 (0.45) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10471396-B2 Fluoropolymers and membranes comprising fluoropolymers (I) PALL CORPORATION (US) 2019-11-12 US disclosed
US-10343122-B2 2019-07-09 US disclosed
EP-3284759-A1 FLUOROPOLYMERS AND MEMBRANES COMPRISING FLUOROPOLYMERS Pall Corporation (US) 2018-02-21 EP disclosed
US-20180043313-A1 FLUOROPOLYMERS AND MEMBRANES COMPRISING FLUOROPOLYMERS (I) PALL CORPORATION (US) 2018-02-15 US disclosed
US-20180043313-A1 FLUOROPOLYMERS AND MEMBRANES COMPRISING FLUOROPOLYMERS (I) PALL CORPORATION (US) 2018-02-15 US disclosed