Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8621935 | 0.90 | ALDH1A1 (0.39) | ALDH1A1MAPTKDM4EPOLBGAA | |
| SCHEMBL7794936 | 0.83 | ALDH1A1 (0.53) | ALDH1A1MAPTKDM4EPOLBGAA | |
| SCHEMBL18573326 | 0.82 | ALDH1A1 (0.41) | ALDH1A1MAPTKDM4EPOLBGAA | |
| SCHEMBL9639704 | 0.81 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL7790930 | 0.80 | PTPN2 (0.33) | ALDH1A1CA1CA2 | |
| SCHEMBL11953279 | 0.80 | ALDH1A1 (0.42) | ALDH1A1MAPTKDM4EPOLBGAA | |
| SCHEMBL19863549 | 0.79 | PTPN2 (0.33) | ALDH1A1CA1CA2 | |
| SCHEMBL8623184 | 0.79 | PTPN2 (0.33) | ALDH1A1CA1CA2 | |
| SCHEMBL18561111 | 0.78 | ALDH1A1 (0.39) | ALDH1A1MAPTKDM4EPOLBGAA | |
| SCHEMBL16434742 | 0.77 | ALDH1A1 (0.37) | ALDH1A1MAPTKDM4EPOLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-63186709-A | — | — | None | — | — | JP | disclosed |
| EP-0729041-B1 | Water-Absorptive soft contact lens | MENICON CO LTD (JP) | 2001-11-28 | — | — | EP | disclosed |
| US-5741830-A | COPOLYMER OF A FLUORINE CONTAINING STYRENE DERIVATIVE AND N,N-DIMETHYL(METH)ACRYLAMIDE | MENICON CO., LTD. (JP) | 1998-04-21 | — | — | US | disclosed |
| EP-0729041-A2 | Water-Absorptive soft contact lens | Menicon Co., Ltd. (JP) | 1996-08-28 | — | — | EP | disclosed |
| JP-S63186709-A | ALKOXYSILYL GROUP-CONTAINING POLYMER | SAGAMI CHEM RES CENTER | 1988-08-02 | — | — | JP | disclosed |