Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN2 | P17706 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19863549 | 0.99 | PTPN2 (0.33) | PTPN2PTPN1PTPN6ALDH1A1CA1 | |
| SCHEMBL8623184 | 0.99 | PTPN2 (0.33) | PTPN2PTPN1PTPN6ALDH1A1CA1 | |
| SCHEMBL7795363 | 0.83 | ALDH1A1 (0.38) | PTPN2PTPN1PTPN6ALDH1A1 | |
| SCHEMBL1081718 | 0.81 | PTPN2 (0.36) | PTPN2PTPN1PTPN6ALDH1A1CA1 | |
| SCHEMBL7790933 | 0.80 | ALDH1A1 (0.37) | ALDH1A1CA1CA2 | |
| SCHEMBL25513628 | 0.80 | ALDH1A1 (0.38) | ALDH1A1CA1CA2 | |
| SCHEMBL14369391 | 0.79 | CHRNA7 (0.45) | ALDH1A1 | |
| SCHEMBL25513621 | 0.78 | ALDH1A1 (0.37) | ALDH1A1CA1CA2 | |
| SCHEMBL25513624 | 0.78 | ALDH1A1 (0.37) | ALDH1A1CA1CA2 | |
| SCHEMBL10062662 | 0.78 | CA2 (0.39) | PTPN2PTPN1PTPN6ALDH1A1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0729041-B1 | Water-Absorptive soft contact lens | MENICON CO LTD (JP) | 2001-11-28 | — | — | EP | disclosed |
| US-5741830-A | COPOLYMER OF A FLUORINE CONTAINING STYRENE DERIVATIVE AND N,N-DIMETHYL(METH)ACRYLAMIDE | MENICON CO., LTD. (JP) | 1998-04-21 | — | — | US | disclosed |
| EP-0729041-A2 | Water-Absorptive soft contact lens | Menicon Co., Ltd. (JP) | 1996-08-28 | — | — | EP | disclosed |