SCHEMBL19863930

SCHEMBL19863930

CC1(C)OB(c2ccc3c(c2)-c2ccccc2C32c3ccccc3C=Cc3ccc(F)cc32)OC1(C)C

nearest known ligand 0.40

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LPL P06858 4/20 0.40
LIPG Q9Y5X9 4/20 0.40
PDK2 Q15119 2/20 0.35
IDO1 P14902 1/20 0.34
TDO2 P48775 1/20 0.34
PRMT5 O14744 1/20 0.33
WDR77 Q9BQA1 1/20 0.33
ROCK1 Q13464 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19863921 0.91 LPL (0.42) LPLLIPGPRMT5WDR77ROCK1
SCHEMBL19863938 0.88 LPL (0.42) LPLLIPGPRMT5WDR77ROCK1
SCHEMBL15682312 0.86 LPL (0.44) LPLLIPGPRMT5WDR77ROCK1
SCHEMBL19863919 0.83 LPL (0.42) LPLLIPGPRMT5WDR77ROCK1
SCHEMBL19869598 0.83 LPL (0.42) LPLLIPGPRMT5WDR77
SCHEMBL19869599 0.83 LPL (0.36) LPLLIPGPRMT5WDR77
SCHEMBL29603284 0.83 LPL (0.49) LPLLIPGPRMT5WDR77ROCK1
SCHEMBL17780741 0.83 LPL (0.49) LPLLIPGPRMT5WDR77ROCK1
SCHEMBL12181998 0.83 LPL (0.49) LPLLIPGPRMT5WDR77ROCK1
SCHEMBL29602682 0.83 LPL (0.49) LPLLIPGPRMT5WDR77ROCK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10476006-B2 Compound and organic electronic device using the same SHANGHAI NICHEM FINE CHEMICAL CO., LTD. (CN) 2019-11-12 US disclosed
EP-3281936-B1 COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME SHANGHAI NICHEM FINE CHEMICAL CO LTD (CN) 2019-10-09 EP disclosed
US-20180047908-A1 COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME NICHEM FINE TECHNOLOGY CO., LTD. (TW) 2018-02-15 US disclosed
US-20180047908-A1 COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME NICHEM FINE TECHNOLOGY CO., LTD. (TW) 2018-02-15 US disclosed
EP-3281936-A1 COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME Nichem Fine Technology Co., Ltd. (TW) 2018-02-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10476006-B2 Compound and organic electronic device using the same ESR1, AOC2, PIEZO1 LPL 4140/4885LIPG 3182/4885PDK2 1268/4885
US-20180047908-A1 COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME ESR1, AOC2, PIEZO1 LPL 4140/4885LIPG 3182/4885PDK2 1268/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.