Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GNE | Q9Y223 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | JMJD1C | Q15652 | 1/20 | 0.33 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20571533 | 0.85 | MAPT (0.40) | KDM4EMAPTTSHRALOX15TDP1 | |
| SCHEMBL20571711 | 0.81 | GAA (0.39) | KDM4EMAPTOGASPRGAA | |
| SCHEMBL20571845 | 0.81 | P2RX7 (0.43) | KDM4EMAPTTDP1KMT2ALMNA | |
| SCHEMBL22050066 | 0.78 | TP53 (0.39) | KDM4EMAPTTDP1LMNAOGA | |
| SCHEMBL30540616 | 0.76 | PIM1 (0.38) | KDM4EMAPTTSHRKMT2ALMNA | |
| SCHEMBL29775930 | 0.73 | KDM4E (0.38) | KDM4EMAPTTSHRALOX15ACMSD | |
| SCHEMBL14610720 | 0.73 | ITGB3 (0.46) | KDM4EMAPT | |
| SCHEMBL19153670 | 0.72 | UHRF1 (0.41) | KDM4EMAPTTSHRALOX15TDP1 | |
| SCHEMBL31394471 | 0.72 | ALDH1A1 (0.44) | KDM4ETSHRALOX15ACMSDTDP1 | |
| SCHEMBL22235162 | 0.72 | ALDH1A1 (0.44) | KDM4ETSHRALOX15ACMSDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018030550-A1 | HETEROCYCLIC COMPOUNDS WITH AN ROR(GAMMA)T MODULATING ACTIVITY | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-02-15 | — | — | WO | disclosed |