Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VEGFA | P15692 | 6/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 3/20 | 0.31 |
| ▸ | ERN1 | O75460 | 1/20 | 0.31 |
| ▸ | LTK | P29376 | 1/20 | 0.31 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.31 |
| ▸ | MST1R | Q04912 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.31 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MIF | P14174 | 1/20 | 0.30 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19865287 | 0.75 | VEGFA (0.41) | VEGFAEPAS1 | |
| SCHEMBL19865213 | 0.75 | VEGFA (0.45) | VEGFAEPAS1 | |
| SCHEMBL19865445 | 0.73 | EPAS1 (0.49) | VEGFAEPAS1 | |
| SCHEMBL19865466 | 0.71 | EPAS1 (0.52) | VEGFAEPAS1 | |
| SCHEMBL19865328 | 0.70 | EPAS1 (0.51) | VEGFAEPAS1 | |
| SCHEMBL19865284 | 0.69 | ERN1 (0.41) | VEGFAERN1TMIGD3MAPTEPAS1 | |
| SCHEMBL19865245 | 0.66 | VEGFA (0.54) | VEGFAEPAS1 | |
| SCHEMBL19865314 | 0.65 | EPAS1 (0.51) | VEGFAEPAS1 | |
| SCHEMBL19865425 | 0.65 | EPAS1 (0.65) | VEGFAEPAS1 | |
| SCHEMBL19865283 | 0.64 | ERN1 (0.43) | ERN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018031680-A1 | NOVEL COMPOUNDS, USES AND METHODS FOR THEIR PREPARATION | FRONTHERA U.S. PHARMACEUTICALS LLC (US) | 2018-02-15 | — | — | WO | disclosed |