Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19865603 | 0.91 | MAPK1 (0.60) | HIF1AMAPK1TSHRKDM4EADRB2 | |
| SCHEMBL19865604 | 0.88 | MAPK1 (0.54) | HIF1AMAPK1TSHRKDM4EADRB2 | |
| SCHEMBL4568929 | 0.84 | HIF1A (0.58) | HIF1AMAPK1TSHRKDM4EADRB2 | |
| SCHEMBL9123406 | 0.81 | ADRB2 (0.62) | HIF1AMAPK1TSHRADRB2ADRB1 | |
| SCHEMBL2204565 | 0.81 | HIF1A (0.54) | HIF1AMAPK1TSHRKDM4EADRB2 | |
| SCHEMBL29818706 | 0.81 | HIF1A (0.54) | HIF1AMAPK1TSHRKDM4EADRB2 | |
| SCHEMBL18653609 | 0.81 | MAPK1 (0.50) | HIF1AMAPK1TSHRKDM4EADRB2 | |
| SCHEMBL4568899 | 0.79 | HIF1A (0.51) | HIF1AMAPK1TSHRKDM4EADRB2 | |
| SCHEMBL8437540 | 0.79 | LMNA (0.66) | HIF1ATSHRKDM4EADRB2ADRB1 | |
| SCHEMBL8437532 | 0.79 | LMNA (0.66) | HIF1ATSHRKDM4EADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10883016-B2 | Actinic radiation-curable urethane/urea-containing aerospace coatings and sealants | PRC-DESOTO INTERNATIONAL, INC. (US) | 2021-01-05 | — | — | US | disclosed |
| US-20190169465-A1 | ACTINIC RADIATION-CURABLE URETHANE/UREA-CONTAINING AEROSPACE COATINGS AND SEALANTS | PRC-DESOTO INTERNATIONAL, INC. (US) | 2019-06-06 | — | — | US | disclosed |
| WO-2018031532-A1 | ACTINIC RADIATION-CURABLE URETHANE/UREA-CONTAINING AEROSPACE COATINGS AND SEALANTS | PRC-DESOTO INTERNATIONAL, INC. (US) | 2018-02-15 | — | — | WO | disclosed |