Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29595792 | 0.82 | CYP2C9 (0.45) | PPARGARALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL19249693 | 0.82 | CYP2C9 (0.45) | PPARGARALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL18294858 | 0.69 | PTGDR2 (0.53) | KDM4ETSHRPTGDR2PLA2G2A | |
| SCHEMBL16879879 | 0.69 | PTGDR2 (0.53) | KDM4ETSHRPTGDR2PLA2G2ACNR2 | |
| SCHEMBL19865719 | 0.69 | LOXL2 (0.54) | PTGDR2 | |
| SCHEMBL15687530 | 0.66 | ALDH1A1 (0.50) | ALDH1A1KDM4EHPGDMAPTTDP1 | |
| SCHEMBL16880166 | 0.65 | PTGDR2 (0.55) | KDM4ETSHRPTGDR2PLA2G2A | |
| SCHEMBL18294856 | 0.65 | PLA2G2A (0.54) | KDM4ETSHRPTGDR2PLA2G2AHDAC1 | |
| SCHEMBL12472851 | 0.64 | ALDH1A1 (0.74) | ARALDH1A1KDM4EGAAMAPK1 | |
| SCHEMBL16880033 | 0.64 | CNR2 (0.58) | PTGDR2CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017136871-A9 | INDOLE AND AZAINDOLE HALOALLYLAMINE DERIVATIVE INHIBITORS OF LYSYL OXIDASES AND USES THEREOF | PHARMAXIS LTD. (AU) | 2018-02-15 | — | — | WO | disclosed |
| WO-2017136871-A1 | INDOLE AND AZAINDOLE HALOALLYLAMINE DERIVATIVE INHIBITORS OF LYSYL OXIDASES AND USES THEREOF | PHARMAXIS LTD. (AU) | 2017-08-17 | — | — | WO | disclosed |