Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 13/20 | 0.35 |
| ▸ | MMP1 | P03956 | 11/20 | 0.35 |
| ▸ | MMP3 | P08254 | 10/20 | 0.35 |
| ▸ | MMP2 | P08253 | 11/20 | 0.35 |
| ▸ | MMP8 | P22894 | 7/20 | 0.35 |
| ▸ | ADAM17 | P78536 | 6/20 | 0.33 |
| ▸ | MMP13 | P45452 | 3/20 | 0.33 |
| ▸ | MMP7 | P09237 | 2/20 | 0.32 |
| ▸ | MMP14 | P50281 | 2/20 | 0.32 |
| ▸ | TNF | P01375 | 2/20 | 0.32 |
| ▸ | MMP20 | O60882 | 1/20 | 0.32 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.32 |
| ▸ | MMP10 | P09238 | 1/20 | 0.32 |
| ▸ | MMP12 | P39900 | 1/20 | 0.32 |
| ▸ | MMP15 | P51511 | 1/20 | 0.32 |
| ▸ | MMP16 | P51512 | 1/20 | 0.32 |
| ▸ | MMP25 | Q9NPA2 | 1/20 | 0.32 |
| ▸ | MMP26 | Q9NRE1 | 1/20 | 0.32 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.32 |
| ▸ | MMP24 | Q9Y5R2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12859968 | 1.00 | MMP9 (0.35) | MMP9MMP1MMP3MMP2MMP8 | |
| SCHEMBL22966090 | 0.89 | BACE1 (0.35) | MMP9MMP1MMP3MMP2MMP8 | |
| SCHEMBL30116852 | 0.85 | MMP2 (0.36) | MMP9MMP1MMP3MMP2 | |
| SCHEMBL23056409 | 0.84 | — | — | |
| SCHEMBL15187389 | 0.83 | MMP9 (0.37) | MMP9MMP1MMP3MMP2MMP8 | |
| SCHEMBL18123722 | 0.82 | MMP9 (0.38) | MMP9MMP1MMP3MMP2MMP8 | |
| SCHEMBL14161358 | 0.80 | MMP9 (0.36) | MMP9MMP1MMP3MMP2MMP8 | |
| SCHEMBL14731829 | 0.79 | MMP2 (0.38) | MMP9MMP1MMP3MMP2MMP8 | |
| SCHEMBL23056665 | 0.79 | SLC7A5 (0.41) | MMP9MMP1MMP3MMP2MMP8 | |
| SCHEMBL17526955 | 0.79 | BACE1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2855508-B1 | CYCLOSPORIN A ANALOGS | ALLERGAN INC (US) | 2018-02-14 | — | — | EP | disclosed |