Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 5/20 | 0.38 |
| ▸ | MMP2 | P08253 | 5/20 | 0.38 |
| ▸ | MMP8 | P22894 | 4/20 | 0.38 |
| ▸ | MMP1 | P03956 | 4/20 | 0.33 |
| ▸ | MMP3 | P08254 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | CTSB | P07858 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.31 |
| ▸ | CIT | O14578 | 1/20 | 0.30 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23056649 | 0.83 | ALDH1A1 (0.33) | ALDH1A1MAPTMEN1LMNAKMT2A | |
| SCHEMBL30060589 | 0.83 | ALDH1A1 (0.39) | ALDH1A1MAPTMEN1LMNAKMT2A | |
| SCHEMBL19866062 | 0.82 | MMP9 (0.35) | MMP9MMP2MMP8MMP1MMP3 | |
| SCHEMBL12859968 | 0.82 | MMP9 (0.35) | MMP9MMP2MMP8MMP1MMP3 | |
| SCHEMBL14546925 | 0.82 | MMP9 (0.37) | MMP9MMP2MMP8MMP1MMP3 | |
| SCHEMBL19955110 | 0.82 | MMP3 (0.32) | MMP9MMP2MMP8MMP3 | |
| SCHEMBL20664927 | 0.82 | MMP3 (0.32) | MMP9MMP2MMP8MMP3 | |
| SCHEMBL20664934 | 0.82 | MMP3 (0.32) | MMP9MMP2MMP8MMP3 | |
| SCHEMBL19955019 | 0.82 | MMP3 (0.32) | MMP9MMP2MMP8MMP3 | |
| SCHEMBL19955112 | 0.82 | MMP3 (0.32) | MMP9MMP2MMP8MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016160362-A1 | CYCLOSPORINS MODIFIED ON THE MEBMT SIDECHAIN BY HETEROCYCLIC RINGS | ALLERGAN, INC. (US) | 2016-10-06 | — | — | WO | disclosed |