Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19869586 | 0.92 | PDK2 (0.38) | PDK2KDM4EMEN1LMNAMAPT | |
| SCHEMBL19869584 | 0.89 | PDK2 (0.39) | PDK2KDM4EMEN1LMNAMAPT | |
| SCHEMBL19863940 | 0.89 | PDK2 (0.41) | PDK2KDM4EMEN1LMNAMAPT | |
| SCHEMBL20173169 | 0.87 | PDK2 (0.41) | PDK2KDM4EMEN1LMNAMAPT | |
| SCHEMBL17929491 | 0.87 | PDK2 (0.41) | PDK2KDM4EMEN1LMNAMAPT | |
| SCHEMBL20225274 | 0.86 | PDK2 (0.40) | PDK2KDM4EMEN1LMNAMAPT | |
| SCHEMBL19862371 | 0.85 | AHR (0.38) | PDK2KDM4EMEN1MAPTKMT2A | |
| SCHEMBL19862378 | 0.84 | ALDH1A1 (0.36) | PDK2MAPTSMN1; SMN2 | |
| SCHEMBL19862351 | 0.84 | AHR (0.37) | PDK2KDM4EMEN1MAPTKMT2A | |
| SCHEMBL19862365 | 0.84 | ALDH1A1 (0.34) | PDK2MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10693075-B2 | Spiro compound and organic electronic device comprising the same | SHANGHAI NICHEM FINE CHEMICAL CO., LTD. (CN) | 2020-06-23 | — | — | US | disclosed |
| US-20180047907-A1 | COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME | NICHEM FINE TECHNOLOGY CO., LTD. (TW) | 2018-02-15 | — | — | US | disclosed |
| US-20180047907-A1 | COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME | NICHEM FINE TECHNOLOGY CO., LTD. (TW) | 2018-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10693075-B2 | Spiro compound and organic electronic device comprising the same | ESRRA, REN, ESRRB | PDK2 1145/4885KDM4E 1852/4885MEN1 2448/4885 |
| US-20180047907-A1 | COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME | CNKSR1, CBX4, RBX1 | PDK2 2859/4885KDM4E 509/4885MEN1 2204/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.