Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4755464 | 0.92 | TDP1 (0.44) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL15015759 | 0.92 | TDP1 (0.44) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL4755469 | 0.92 | TDP1 (0.44) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL4753769 | 0.87 | ALDH1A1 (0.42) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL15015721 | 0.87 | ALDH1A1 (0.42) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL4753767 | 0.87 | ALDH1A1 (0.42) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL21358002 | 0.85 | GPR84 (0.47) | CA2MAPK1GRIK1GRIK2 | |
| SCHEMBL8320640 | 0.83 | TDP1 (0.59) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL234751 | 0.83 | ALDH1A1 (0.46) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL235849 | 0.82 | ALDH1A1 (0.50) | ALDH1A1LMNAHSD17B10ALOX15PIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3034535-B1 | EPOXY RESIN CONTAINING SILICONE-MODIFIED EPOXY RESIN AND POLYVALENT CARBOXYLIC ACID COMPOUND, AND CURED PRODUCT THEREOF | SHINETSU CHEMICAL CO (JP) | 2018-02-14 | — | — | EP | disclosed |