Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4755464 | 1.00 | TDP1 (0.44) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL15015759 | 1.00 | TDP1 (0.44) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL19873006 | 0.92 | TDP1 (0.46) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL234751 | 0.91 | ALDH1A1 (0.46) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL15015749 | 0.88 | CA2 (0.45) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL15015525 | 0.88 | CA2 (0.45) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL15015736 | 0.85 | HDAC1 (0.43) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL27958014 | 0.84 | GPR84 (0.50) | ALDH1A1GRIK1GRIK2 | |
| SCHEMBL14110749 | 0.83 | TDP1 (0.60) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL5031485 | 0.83 | TDP1 (0.60) | TDP1CHRM1AKR1A1CHRM3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3034535-B1 | EPOXY RESIN CONTAINING SILICONE-MODIFIED EPOXY RESIN AND POLYVALENT CARBOXYLIC ACID COMPOUND, AND CURED PRODUCT THEREOF | SHINETSU CHEMICAL CO (JP) | 2018-02-14 | — | — | EP | disclosed |
| CN-102159596-B | Solid catalyst component and catalyst for polymerization of olefins, and process for production of olefin polymers using same | TOHO TITANIUM CO LTD | 2014-05-07 | — | — | CN | disclosed |
| EP-2604634-A1 | CATALYST COMPONENT FOR OLEFIN POLYMERIZATION REACTION AND CATALYST THEREOF | China Petroleum & Chemical Corporation (CN) | 2013-06-19 | — | — | EP | disclosed |
| CN-102159596-A | Solid catalyst component and catalyst for polymerization of olefins, and process for production of olefin polymers using same | TOHO TITANIUM CO LTD | 2011-08-17 | — | — | CN | disclosed |
| WO-2008155619-A2 | PREPARATION OF OPTICALLY-ACTIVE CYCLIC AMINO ACIDS | PFIZER INC. (US) | 2008-12-24 | — | — | WO | disclosed |