SCHEMBL1987331

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL31222430	1.00	ALDH1A1 (0.58)	ALDH1A1HSD17B10TSHRMAPK1L3MBTL1
	SCHEMBL24901117	0.85	MAPK1 (0.52)	ALDH1A1HSD17B10TSHRMAPK1L3MBTL1
	SCHEMBL25124897	0.85	ALDH1A1 (0.52)	ALDH1A1HSD17B10TSHRMAPK1L3MBTL1
	SCHEMBL21326203	0.84	ALDH1A1 (0.50)	ALDH1A1HSD17B10TSHRMAPK1L3MBTL1
	SCHEMBL30075955	0.84	ALDH1A1 (0.50)	ALDH1A1HSD17B10TSHRMAPK1L3MBTL1
	SCHEMBL27295403	0.83	ALDH1A1 (0.42)	ALDH1A1HSD17B10TSHRMAPK1L3MBTL1
	SCHEMBL12200359	0.83	ALDH1A1 (0.44)	ALDH1A1HSD17B10TSHRMAPK1L3MBTL1
	SCHEMBL25125276	0.82	ALDH1A1 (0.48)	ALDH1A1HSD17B10TSHRMAPK1L3MBTL1
	SCHEMBL21368245	0.81	ALDH1A1 (0.47)	ALDH1A1HSD17B10TSHRMAPK1L3MBTL1
	SCHEMBL23008124	0.81	MAPK1 (0.39)	ALDH1A1HSD17B10TSHRMAPK1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.