Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 1/20 | 0.36 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 7/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | CDK13 | Q14004 | 1/20 | 0.30 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19873634 | 0.90 | LPAR1 (0.38) | LPAR1LPAR3NAAAENPP2 | |
| SCHEMBL19873601 | 0.90 | LPAR1 (0.38) | LPAR1LPAR3NAAAENPP2 | |
| SCHEMBL19873636 | 0.89 | LPAR1 (0.46) | LPAR1LPAR3DGAT1NAAA | |
| SCHEMBL19873635 | 0.89 | LPAR1 (0.46) | LPAR1LPAR3DGAT1NAAA | |
| SCHEMBL28387786 | 0.88 | MEN1 (0.31) | — | |
| SCHEMBL19873626 | 0.87 | DGAT1 (0.33) | LPAR1LPAR3DGAT1IDO1ENPP2 | |
| SCHEMBL17367451 | 0.86 | LPAR1 (0.36) | LPAR1LPAR3 | |
| SCHEMBL17215491 | 0.86 | LPAR1 (0.42) | LPAR1LPAR3 | |
| SCHEMBL19873555 | 0.84 | LPAR1 (0.34) | LPAR1LPAR3NAAA | |
| SCHEMBL19873553 | 0.84 | LPAR1 (0.34) | LPAR1LPAR3NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3360869-B1 | HALOGEN-SUBSTITUTED HETEROCYCLIC COMPOUND USEFUL FOR THE TREATMENT OF DISEASES CAUSED BY LPA. | UBE INDUSTRIES (JP) | 2020-07-29 | — | — | EP | claimed |
| EP-2940013-B1 | HALOGEN-SUBSTITUTED HETEROCYCLIC COMPOUND | UBE INDUSTRIES (JP) | 2018-02-21 | — | — | EP | claimed |