Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
| ▸ | TDO2 | P48775 | 1/20 | 0.30 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25191490 | 0.88 | JAK2 (0.32) | ROCK1 | |
| SCHEMBL21058443 | 0.84 | AAK1 (0.35) | — | |
| SCHEMBL17504507 | 0.83 | JAK2 (0.31) | PTGDR2ROCK1 | |
| SCHEMBL16990403 | 0.75 | LPL (0.36) | IDO1TDO2ROCK1 | |
| SCHEMBL25252247 | 0.73 | — | — | |
| SCHEMBL30369811 | 0.72 | BACE1 (0.33) | — | |
| SCHEMBL25174282 | 0.72 | BACE1 (0.33) | — | |
| SCHEMBL25180376 | 0.72 | JAK2 (0.35) | ROCK1 | |
| SCHEMBL22119838 | 0.69 | LPL (0.37) | — | |
| SCHEMBL29363705 | 0.69 | GPR119 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018033082-A1 | INHIBITORS OF INFLUENZA VIRUS REPLICATION, APPLICATION METHODS AND USES THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2018-02-22 | — | — | WO | disclosed |