⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25028792 | 0.85 | USP30 (0.33) | — | |
| SCHEMBL29005554 | 0.79 | ELANE (0.33) | — | |
| SCHEMBL25029242 | 0.73 | PRMT5 (0.33) | — | |
| SCHEMBL29363521 | 0.73 | PRMT5 (0.33) | — | |
| SCHEMBL19876637 | 0.73 | PTGDR2 (0.31) | — | |
| SCHEMBL25029112 | 0.72 | BACE1 (0.34) | — | |
| SCHEMBL17504507 | 0.71 | JAK2 (0.31) | — | |
| SCHEMBL30673620 | 0.70 | UCHL1 (0.33) | — | |
| SCHEMBL31104104 | 0.69 | JAK2 (0.36) | — | |
| SCHEMBL22119838 | 0.69 | LPL (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4182320-A1 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | Nido Biosciences, Inc. (US) | 2023-05-24 | — | — | EP | disclosed |
| WO-2022020342-A1 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | NIDO BIOSCIENCES, INC. (US) | 2022-01-27 | — | — | WO | disclosed |