Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | CASP1 | P29466 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.32 |
| ▸ | RBP4 | P02753 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | SLC6A15 | Q9H2J7 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29774758 | 0.92 | MAPT (0.32) | MAPTALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL21796215 | 0.92 | MAPT (0.32) | MAPTALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL18498690 | 0.89 | NOTUM (0.40) | MAPTALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL31141489 | 0.89 | NOTUM (0.40) | MAPTALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL18498705 | 0.84 | POLB (0.33) | MAPTALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL18506249 | 0.84 | DDR1 (0.35) | MAPTALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL19876693 | 0.82 | MAPT (0.37) | MAPTALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL19876691 | 0.79 | PDE2A (0.33) | PDE2AHTT | |
| SCHEMBL29720545 | 0.79 | PDE2A (0.33) | PDE2AHTT | |
| SCHEMBL19876978 | 0.79 | CYP11B1 (0.39) | CYP11B2PDE2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10875858-B2 | Process for preparing halogenated pyridine derivatives | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-12-29 | — | — | US | disclosed |
| US-10875858-B2 | Process for preparing halogenated pyridine derivatives | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-12-29 | — | — | US | disclosed |
| EP-3500568-B1 | PROCESS FOR THE PREPARATION OF 2-(3,6-DIHALOPYRIDIN-2-YL)-3H-IMIDAZOL[4,5-C]PYRIDINE DERIVATIVES AND RELATED COMPOUNDS BY REACTING THE 3H-IMIDAZOL[4,5-C]PYRIDINE DERIVATIVE WITH A METAL-ORGANIC ZINC-AMINE BASE | BAYER CROPSCIENCE AG (DE) | 2020-09-23 | — | — | EP | disclosed |
| US-20190202829-A1 | PROCESS FOR PREPARING HALOGENATED PYRIDINE DERIVATIVES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-07-04 | — | — | US | disclosed |
| US-20190202829-A1 | PROCESS FOR PREPARING HALOGENATED PYRIDINE DERIVATIVES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-07-04 | — | — | US | disclosed |
| EP-3500568-A1 | METHOD FOR PRODUCING 2-(3,6-DIHALOPYRIDIN-2-YL)-3H-IMIDAZOL[4,5-C]PYRIDINE DERIVATIVES AND RELATED COMPOUNDS BY REACTION OF THE 3H-IMIDAZOL[4,5-C]PYRIDINE DERIVATIVE WITH AN ORGANOMETALLIC ZINC-AMINE BASE | Bayer CropScience Aktiengesellschaft (DE) | 2019-06-26 | — | — | EP | disclosed |
| WO-2018033448-A1 | METHOD FOR PRODUCING 2-(3,6-DIHALOPYRIDIN-2-YL)-3H-IMIDAZOL[4,5-C]PYRIDINE DERIVATIVES AND RELATED COMPOUNDS BY REACTION OF THE 3H-IMIDAZOL[4,5-C]PYRIDINE DERIVATIVE WITH AN ORGANOMETALLIC ZINC-AMINE BASE | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-02-22 | — | — | WO | disclosed |
| WO-2018033448-A1 | METHOD FOR PRODUCING 2-(3,6-DIHALOPYRIDIN-2-YL)-3H-IMIDAZOL[4,5-C]PYRIDINE DERIVATIVES AND RELATED COMPOUNDS BY REACTION OF THE 3H-IMIDAZOL[4,5-C]PYRIDINE DERIVATIVE WITH AN ORGANOMETALLIC ZINC-AMINE BASE | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-02-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10875858-B2 | Process for preparing halogenated pyridine derivatives | CBR3, NQO2, CBR1 | MAPT 4568/4885ALDH1A1 3359/4885KDM4E 754/4885 |
| US-20190202829-A1 | PROCESS FOR PREPARING HALOGENATED PYRIDINE DERIVATIVES | CBR3, NQO2, CBR1 | MAPT 4568/4885ALDH1A1 3359/4885KDM4E 754/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.