Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | SLC6A15 | Q9H2J7 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | SDHB | P21912 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21796207 | 0.93 | SLC6A15 (0.32) | POLBKDM4EALDH1A1TSHRHSD17B10 | |
| SCHEMBL29774753 | 0.93 | SLC6A15 (0.32) | POLBKDM4EALDH1A1TSHRHSD17B10 | |
| SCHEMBL19877212 | 0.84 | MAPT (0.37) | KDM4EALDH1A1TSHRHSD17B10SLC6A15 | |
| SCHEMBL18506138 | 0.84 | POLB (0.51) | POLBMAPTMRGPRX4LMNAL3MBTL1 | |
| SCHEMBL18498690 | 0.84 | NOTUM (0.40) | KDM4EALDH1A1SLC6A15MAPTHPGD | |
| SCHEMBL31141489 | 0.84 | NOTUM (0.40) | KDM4EALDH1A1SLC6A15MAPTHPGD | |
| SCHEMBL18506249 | 0.83 | DDR1 (0.35) | KDM4EALDH1A1HSD17B10SLC6A15MAPT | |
| SCHEMBL28359602 | 0.82 | ACVR1 (0.31) | POLBALDH1A1MAPTLMNA | |
| SCHEMBL29720572 | 0.82 | ACVR1 (0.31) | POLBALDH1A1MAPTLMNA | |
| SCHEMBL21930788 | 0.81 | ALDH1A1 (0.31) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3896066-A2 | 2-(HET)ARYL-SUBSTITUTED CONDENSED HETEROCYCLE DERIVATIVES AS PESTICIDES | Bayer CropScience Aktiengesellschaft (DE) | 2021-10-20 | — | — | EP | disclosed |
| EP-3896065-A1 | 2-(HET)ARYL-SUBSTITUTED CONDENSED HETEROCYCLE DERIVATIVES AS PESTICIDES | Bayer CropScience Aktiengesellschaft (DE) | 2021-10-20 | — | — | EP | disclosed |
| EP-3331870-B1 | 2-(HET)ARYL-SUBSTITUTED CONDENSED HETEROCYCLE DERIVATIVES AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2021-06-16 | — | — | EP | disclosed |
| US-10986840-B2 | 2-(het)aryl-substituted fused heterocycle derivatives as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2021-04-27 | — | — | US | disclosed |
| US-10667517-B2 | 2-(Het)aryl-substituted fused heterocycle derivatives as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-06-02 | — | — | US | disclosed |
| US-20200029567-A1 | 2-(Het)aryl-substituted fused heterocycle derivatives as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-01-30 | — | — | US | disclosed |
| US-20180271099-A1 | 2-(Het)aryl-substituted fused heterocycle derivatives as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-09-27 | — | — | US | disclosed |
| EP-3331870-A2 | 2-(HET)ARYL-SUBSTITUTED CONDENSED HETEROCYCLIC DERIVATIVES AS PEST CONTROL AGENTS | Bayer CropScience Aktiengesellschaft (DE) | 2018-06-13 | — | — | EP | disclosed |
| WO-2017025419-A2 | 2-(HET)ARYL-SUBSTITUTED CONDENSED HETEROCYCLIC DERIVATIVES AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-02-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10667517-B2 | 2-(Het)aryl-substituted fused heterocycle derivatives as pesticides | CYP1A1, CYP8B1, CYP1B1 | POLB 4837/4885KDM4E 2736/4885ALDH1A1 268/4885 |
| US-20200029567-A1 | 2-(Het)aryl-substituted fused heterocycle derivatives as pesticides | CYP1A1, CYP8B1, CYP1B1 | POLB 4837/4885KDM4E 2736/4885ALDH1A1 268/4885 |
| US-10986840-B2 | 2-(het)aryl-substituted fused heterocycle derivatives as pesticides | CYP1A1, CYP8B1, CYP1B1 | POLB 4837/4885KDM4E 2736/4885ALDH1A1 268/4885 |
| US-20180271099-A1 | 2-(Het)aryl-substituted fused heterocycle derivatives as pesticides | CYP1A1, CYP8B1, CYP1B1 | POLB 4837/4885KDM4E 2736/4885ALDH1A1 268/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.