Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | ENPP1 | P22413 | 3/20 | 0.34 |
| ▸ | DHODH | Q02127 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17967742 | 0.85 | DDR1 (0.35) | MAPTALDH1A1HPGDKDM4ESCN9A | |
| SCHEMBL31534710 | 0.85 | DDR1 (0.35) | MAPTALDH1A1HPGDKDM4ESCN9A | |
| SCHEMBL19877212 | 0.82 | MAPT (0.37) | MAPTALDH1A1HPGDKDM4EMRGPRX4 | |
| SCHEMBL17967736 | 0.81 | USP1 (0.33) | DHODHCYP11B2ALOX5AP | |
| SCHEMBL19876690 | 0.79 | DGAT1 (0.32) | MAPTDHODHALDH1A1CYP11B2SMN1; SMN2 | |
| SCHEMBL19876689 | 0.79 | MEN1 (0.36) | DHODHALDH1A1HPGDKDM4ECYP11B2 | |
| SCHEMBL19876688 | 0.77 | MEN1 (0.33) | DHODHALDH1A1KDM4ESMN1; SMN2RAB9A | |
| SCHEMBL21796215 | 0.77 | MAPT (0.32) | MAPTALDH1A1HPGDKDM4ECYP11B2 | |
| SCHEMBL29774758 | 0.77 | MAPT (0.32) | MAPTALDH1A1HPGDKDM4ECYP11B2 | |
| SCHEMBL20379046 | 0.75 | SDHB (0.34) | MAPTENPP1ALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10875858-B2 | Process for preparing halogenated pyridine derivatives | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-12-29 | — | — | US | disclosed |
| US-10875858-B2 | Process for preparing halogenated pyridine derivatives | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-12-29 | — | — | US | disclosed |
| EP-3500568-B1 | PROCESS FOR THE PREPARATION OF 2-(3,6-DIHALOPYRIDIN-2-YL)-3H-IMIDAZOL[4,5-C]PYRIDINE DERIVATIVES AND RELATED COMPOUNDS BY REACTING THE 3H-IMIDAZOL[4,5-C]PYRIDINE DERIVATIVE WITH A METAL-ORGANIC ZINC-AMINE BASE | BAYER CROPSCIENCE AG (DE) | 2020-09-23 | — | — | EP | disclosed |
| EP-3500568-B1 | PROCESS FOR THE PREPARATION OF 2-(3,6-DIHALOPYRIDIN-2-YL)-3H-IMIDAZOL[4,5-C]PYRIDINE DERIVATIVES AND RELATED COMPOUNDS BY REACTING THE 3H-IMIDAZOL[4,5-C]PYRIDINE DERIVATIVE WITH A METAL-ORGANIC ZINC-AMINE BASE | BAYER CROPSCIENCE AG (DE) | 2020-09-23 | — | — | EP | disclosed |
| US-20190202829-A1 | PROCESS FOR PREPARING HALOGENATED PYRIDINE DERIVATIVES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-07-04 | — | — | US | disclosed |
| US-20190202829-A1 | PROCESS FOR PREPARING HALOGENATED PYRIDINE DERIVATIVES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-07-04 | — | — | US | disclosed |
| EP-3500568-A1 | METHOD FOR PRODUCING 2-(3,6-DIHALOPYRIDIN-2-YL)-3H-IMIDAZOL[4,5-C]PYRIDINE DERIVATIVES AND RELATED COMPOUNDS BY REACTION OF THE 3H-IMIDAZOL[4,5-C]PYRIDINE DERIVATIVE WITH AN ORGANOMETALLIC ZINC-AMINE BASE | Bayer CropScience Aktiengesellschaft (DE) | 2019-06-26 | — | — | EP | disclosed |
| WO-2018033448-A1 | METHOD FOR PRODUCING 2-(3,6-DIHALOPYRIDIN-2-YL)-3H-IMIDAZOL[4,5-C]PYRIDINE DERIVATIVES AND RELATED COMPOUNDS BY REACTION OF THE 3H-IMIDAZOL[4,5-C]PYRIDINE DERIVATIVE WITH AN ORGANOMETALLIC ZINC-AMINE BASE | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-02-22 | — | — | WO | disclosed |
| WO-2018033448-A1 | METHOD FOR PRODUCING 2-(3,6-DIHALOPYRIDIN-2-YL)-3H-IMIDAZOL[4,5-C]PYRIDINE DERIVATIVES AND RELATED COMPOUNDS BY REACTION OF THE 3H-IMIDAZOL[4,5-C]PYRIDINE DERIVATIVE WITH AN ORGANOMETALLIC ZINC-AMINE BASE | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-02-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10875858-B2 | Process for preparing halogenated pyridine derivatives | CBR3, NQO2, CBR1 | MAPT 4568/4885ENPP1 2337/4885DHODH 1388/4885 |
| US-20190202829-A1 | PROCESS FOR PREPARING HALOGENATED PYRIDINE DERIVATIVES | CBR3, NQO2, CBR1 | MAPT 4568/4885ENPP1 2337/4885DHODH 1388/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.