Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | STS | P08842 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19889338 | 0.89 | KDM4E (0.48) | KDM4EALDH1A1PKMMAPTPOLB | |
| SCHEMBL453426 | 0.88 | APP (0.49) | KDM4EALDH1A1PKMMAPTPOLB | |
| SCHEMBL19889041 | 0.86 | MAPK1 (0.48) | KDM4EALDH1A1PKMMAPTPOLB | |
| SCHEMBL18422997 | 0.84 | ALDH1A1 (0.56) | KDM4EALDH1A1PKMMAPTPOLB | |
| SCHEMBL17914090 | 0.84 | PKM (0.43) | KDM4EALDH1A1PKMMAPTPOLB | |
| SCHEMBL29574618 | 0.83 | KDM4E (0.53) | KDM4EALDH1A1MAPTPOLBSMN1; SMN2 | |
| SCHEMBL19876825 | 0.83 | KDM4E (0.53) | KDM4EALDH1A1MAPTPOLBSMN1; SMN2 | |
| SCHEMBL7834117 | 0.83 | PKM (0.60) | KDM4EALDH1A1PKMMAPTPOLB | |
| SCHEMBL15392053 | 0.82 | MAPT (0.61) | KDM4EALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL10397250 | 0.82 | MAPT (0.61) | KDM4EALDH1A1MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11649222-B2 | Compounds | UNIVERSITETET I OSLO (NO) | 2023-05-16 | — | — | US | disclosed |
| US-11649222-B2 | Compounds | UNIVERSITETET I OSLO (NO) | 2023-05-16 | — | — | US | disclosed |
| US-11649222-B2 | Compounds | UNIVERSITETET I OSLO (NO) | 2023-05-16 | — | — | US | disclosed |
| EP-3978488-A1 | ZINC CHELATING COMPOUNDS FOR USE IN THE TREATMENT OF BACTERIAL INFECTION | Universitetet I Oslo (NO) | 2022-04-06 | — | — | EP | disclosed |
| EP-3978488-A1 | ZINC CHELATING COMPOUNDS FOR USE IN THE TREATMENT OF BACTERIAL INFECTION | Universitetet I Oslo (NO) | 2022-04-06 | — | — | EP | disclosed |
| CN-109952297-B | Compound (I) | 奥斯陆大学 | 2022-02-25 | — | — | CN | disclosed |
| US-20210221791-A1 | COMPOUNDS | UNIVERSITETET I OSLO (NO) | 2021-07-22 | — | — | US | disclosed |
| US-20210221791-A1 | COMPOUNDS | UNIVERSITETET I OSLO (NO) | 2021-07-22 | — | — | US | disclosed |
| EP-3497095-B1 | ZINC CHELATING COMPOUNDS FOR USE IN THE TREATMENT OF BACTERIAL INFECTION | UNIV OSLO (NO) | 2021-07-14 | — | — | EP | disclosed |
| EP-3497095-B1 | ZINC CHELATING COMPOUNDS FOR USE IN THE TREATMENT OF BACTERIAL INFECTION | UNIV OSLO (NO) | 2021-07-14 | — | — | EP | disclosed |
| US-10961223-B2 | Compounds | UNIVERSITETET I OSLO (NO) | 2021-03-30 | — | — | US | disclosed |
| US-10961223-B2 | Compounds | UNIVERSITETET I OSLO (NO) | 2021-03-30 | — | — | US | disclosed |
| US-20190284167-A1 | COMPOUNDS | UNIVERSITETET I OSLO (NO) | 2019-09-19 | — | — | US | disclosed |
| US-20190284167-A1 | COMPOUNDS | UNIVERSITETET I OSLO (NO) | 2019-09-19 | — | — | US | disclosed |
| CN-109952297-A | Compound | 奥斯陆大学 | 2019-06-28 | — | — | CN | disclosed |
| EP-3497095-A1 | COMPOUNDS | Universitetet I Oslo (NO) | 2019-06-19 | — | — | EP | disclosed |
| WO-2018033719-A1 | COMPOUNDS | UNIVERSITETET I OSLO (NO) | 2018-02-22 | — | — | WO | disclosed |
| WO-2018033719-A1 | COMPOUNDS | UNIVERSITETET I OSLO (NO) | 2018-02-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11649222-B2 | Compounds | SLC30A6, SLC39A11, SLC39A3 | KDM4E 2941/4885ALDH1A1 3235/4885PKM 2850/4885 |
| US-10961223-B2 | Compounds | SLC30A6, SLC39A11, SLC30A5 | KDM4E 2847/4885ALDH1A1 2991/4885PKM 2571/4885 |
| US-20190284167-A1 | COMPOUNDS | SLC30A6, SLC39A11, SLC30A5 | KDM4E 2847/4885ALDH1A1 2991/4885PKM 2571/4885 |
| US-20210221791-A1 | COMPOUNDS | SLC30A6, SLC30A5, SLC39A11 | KDM4E 2313/4885ALDH1A1 4328/4885PKM 3373/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.