Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | STS | P08842 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19878024 | 0.88 | KDM4E (0.56) | MAPTSMN1; SMN2LIN28ATDP1PKM | |
| SCHEMBL469430 | 0.85 | APP (0.52) | APPMAPTSMN1; SMN2LIN28ATDP1 | |
| SCHEMBL453317 | 0.83 | APP (0.56) | APPMAPTSMN1; SMN2LIN28ATDP1 | |
| SCHEMBL19889041 | 0.83 | MAPK1 (0.48) | MAPTSMN1; SMN2LIN28ATDP1PKM | |
| SCHEMBL19889338 | 0.83 | KDM4E (0.48) | MAPTSMN1; SMN2LIN28ATDP1PKM | |
| SCHEMBL17914090 | 0.83 | PKM (0.43) | APPMAPTSMN1; SMN2PKMALDH1A1 | |
| SCHEMBL17285718 | 0.80 | KDM4E (0.42) | MAPTPKMALDH1A1KDM4EHPGD | |
| SCHEMBL15810346 | 0.79 | MAPT (0.53) | APPMAPTSMN1; SMN2LIN28ATDP1 | |
| SCHEMBL17285715 | 0.79 | KDM5B (0.46) | SMN1; SMN2TDP1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL29575263 | 0.77 | ALDH1A1 (0.52) | MAPTSMN1; SMN2LIN28ATDP1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9377466-B2 | Compounds and methods | MODPRO AB (SE) | 2016-06-28 | — | — | US | disclosed |
| US-20130261013-A1 | Compounds and Methods | MODPRO AB (SE) | 2013-10-03 | — | — | US | disclosed |
| EP-2613796-A2 | COMPOUNDS AND METHODS | Modpro AB (SE) | 2013-07-17 | — | — | EP | disclosed |
| WO-2012032068-A2 | COMPOUNDS AND METHODS | MODPRO AB (SE) | 2012-03-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130261013-A1 | Compounds and Methods | NOS2, NOS1, NOS3 | APP 1544/4885MAPT 2920/4885SMN1; SMN2 3681/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.