Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.54 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 3/20 | 0.41 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | BRD4 | O60885 | 4/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.38 |
| ▸ | RXRB | P28702 | 2/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | HPD | P32754 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6121759 | 0.86 | MRGPRX4 (0.54) | MRGPRX4ADRB2ADRB1ADRB3HTR1A | |
| SCHEMBL5101144 | 0.74 | MRGPRX4 (0.74) | MRGPRX4ADRB2ADRB1ADRB3HTR1A | |
| SCHEMBL31318410 | 0.74 | MRGPRX4 (0.74) | MRGPRX4ADRB2ADRB1ADRB3HTR1A | |
| SCHEMBL8753959 | 0.74 | MRGPRX4 (0.57) | MRGPRX4ADRB2ADRB1ADRB3HTR1A | |
| SCHEMBL18829235 | 0.73 | MRGPRX4 (0.53) | MRGPRX4ADRB2ADRB1ADRB3HTR1A | |
| SCHEMBL5270656 | 0.72 | MRGPRX4 (0.56) | MRGPRX4ADRB2ADRB1ADRB3HTR1A | |
| SCHEMBL11806193 | 0.71 | MRGPRX4 (0.53) | MRGPRX4ADRB2ADRB1ADRB3HTR1A | |
| SCHEMBL22480543 | 0.70 | MRGPRX4 (1.00) | MRGPRX4RXRBRXRAHPGDPOLB | |
| SCHEMBL21821534 | 0.70 | MRGPRX4 (0.54) | MRGPRX4ADRB2ADRB1ADRB3HTR1A | |
| SCHEMBL30317439 | 0.70 | MRGPRX4 (0.54) | MRGPRX4ADRB2ADRB1ADRB3HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3284741-A1 | ANTIVIRAL COMPOUNDS | Gilead Pharmasset LLC (US) | 2018-02-21 | — | — | EP | disclosed |