Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.57 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.41 |
| ▸ | BRD4 | O60885 | 4/20 | 0.40 |
| ▸ | RXRB | P28702 | 6/20 | 0.40 |
| ▸ | RXRA | P19793 | 6/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | PRKCI | P41743 | 1/20 | 0.40 |
| ▸ | RXRG | P48443 | 3/20 | 0.36 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.36 |
| ▸ | BRAF | P15056 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18829235 | 0.87 | MRGPRX4 (0.53) | MRGPRX4ADRB2ADRB1ADRB3HTR1A | |
| SCHEMBL31318410 | 0.74 | MRGPRX4 (0.74) | MRGPRX4ADRB2ADRB1ADRB3HTR1A | |
| SCHEMBL5101144 | 0.74 | MRGPRX4 (0.74) | MRGPRX4ADRB2ADRB1ADRB3HTR1A | |
| SCHEMBL19883576 | 0.74 | MRGPRX4 (0.54) | MRGPRX4ADRB2ADRB1ADRB3HTR1A | |
| SCHEMBL6121759 | 0.74 | MRGPRX4 (0.54) | MRGPRX4ADRB2ADRB1ADRB3HTR1A | |
| SCHEMBL22480543 | 0.72 | MRGPRX4 (1.00) | MRGPRX4RXRBRXRARXRGPTGER1 | |
| SCHEMBL5270656 | 0.72 | MRGPRX4 (0.56) | MRGPRX4ADRB2ADRB1ADRB3HTR1A | |
| SCHEMBL1839684 | 0.71 | MRGPRX4 (0.63) | MRGPRX4ADRB2ADRB1ADRB3HTR1A | |
| SCHEMBL21821534 | 0.70 | MRGPRX4 (0.54) | MRGPRX4ADRB2ADRB1ADRB3HTR1A | |
| SCHEMBL30317439 | 0.70 | MRGPRX4 (0.54) | MRGPRX4ADRB2ADRB1ADRB3HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012068234-A2 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2012-05-24 | — | — | WO | disclosed |