Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 8/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.57 |
| ▸ | GRM2 | Q14416 | 4/20 | 0.57 |
| ▸ | GRM3 | Q14832 | 3/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | GRM8 | O00222 | 2/20 | 0.57 |
| ▸ | GRM6 | O15303 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | GRM5 | P41594 | 1/20 | 0.57 |
| ▸ | MTOR | P42345 | 1/20 | 0.57 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.57 |
| ▸ | PLCB1 | Q9NQ66 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27595459 | 0.85 | GRM4 (0.76) | GRM4CYP1A2GRM2GRM3ALOX15 | |
| Cycloleucine SCHEMBL21462057 | 0.82 | NSD2 (0.50) | GRM4CYP1A2GRM2GRM3ALOX15 | |
| Cycloleucine SCHEMBL8495 | 0.82 | — | — | |
| SCHEMBL7271016 | 0.82 | GRM4 (0.78) | GRM4CYP1A2GRM2GRM3ALOX15 | |
| SCHEMBL4835681 | 0.82 | GRM4 (0.78) | GRM4CYP1A2GRM2GRM3ALOX15 | |
| SCHEMBL2916853 | 0.82 | GRM4 (0.78) | GRM4CYP1A2GRM2GRM3ALOX15 | |
| Cycloleucine SCHEMBL3164459 | 0.79 | NSD2 (0.48) | GRM4CYP1A2GRM2GRM3ALOX15 | |
| SCHEMBL21423145 | 0.79 | NSD2 (0.48) | GRM4CYP1A2GRM2GRM3ALOX15 | |
| Cycloleucine SCHEMBL1711763 | 0.79 | NSD2 (0.48) | GRM4CYP1A2GRM2GRM3ALOX15 | |
| SCHEMBL744894 | 0.79 | NSD2 (0.48) | GRM4CYP1A2GRM2GRM3ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8546533-B2 | Pipecolic linker and its use for chemistry on solid support | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2013-10-01 | — | — | US | disclosed |
| US-20110152464-A1 | PIPECOLIC LINKER AND ITS USE FOR CHEMISTRY ON SOLID SUPPORT | UNIVERSITE DE MONTPELLIER I (FR) | 2011-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152464-A1 | PIPECOLIC LINKER AND ITS USE FOR CHEMISTRY ON SOLID SUPPORT | PRRC2C, VIP, PRRC2A | GRM4 4657/4885CYP1A2 4401/4885GRM2 4734/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.