Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 1/20 | 0.48 |
| ▸ | GRM4 | Q14833 | 8/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | GRM8 | O00222 | 2/20 | 0.44 |
| ▸ | GRM6 | O15303 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.43 |
| ▸ | GRM3 | Q14832 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 1-Aminocyclobutane Carboxylic Acid SCHEMBL61734 | 0.97 | — | — | |
| Cycloleucine SCHEMBL8495 | 0.97 | — | — | |
| Cycloleucine SCHEMBL21462057 | 0.97 | NSD2 (0.50) | NSD2GRM4CYP2C19CYP1A2ALOX15 | |
| SCHEMBL62221 | 0.94 | NSD2 (0.48) | NSD2GRM4CYP2C19CYP1A2ALOX15 | |
| Cycloleucine SCHEMBL1704308 | 0.94 | NSD2 (0.48) | NSD2GRM4CYP2C19CYP1A2ALOX15 | |
| Cycloleucine SCHEMBL1711763 | 0.94 | NSD2 (0.48) | NSD2GRM4CYP2C19CYP1A2ALOX15 | |
| SCHEMBL744894 | 0.94 | NSD2 (0.48) | NSD2GRM4CYP2C19CYP1A2ALOX15 | |
| SCHEMBL21423145 | 0.94 | NSD2 (0.48) | NSD2GRM4CYP2C19CYP1A2ALOX15 | |
| Cycloleucine SCHEMBL3674853 | 0.94 | NSD2 (0.48) | NSD2GRM4CYP2C19CYP1A2ALOX15 | |
| 1-Aminocyclobutane Carboxylic Acid SCHEMBL4949098 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1704165-B1 | GLP-1 COMPOUNDS | NOVO NORDISK AS (DK) | 2010-03-17 | — | — | EP | disclosed |
| US-6544949-B1 | Administering peptide or its derivative for therapy of osteoporosis | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES, S.A.S. (FR) | 2003-04-08 | — | — | US | disclosed |