SCHEMBL19888

SCHEMBL19888

O=C1[N]C(=O)c2ccccc21

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 3/20 0.50
▸ KMT2A Q03164 3/20 0.50
▸ CDC25B P30305 2/20 0.50
▸ MAOA P21397 3/20 0.47
▸ TDP2 O95551 3/20 0.47
▸ APAF1 O14727 2/20 0.47
▸ POLB P06746 2/20 0.47
▸ S100A4 P26447 2/20 0.47
▸ MAPK1 P28482 2/20 0.47
▸ RECQL P46063 2/20 0.47
▸ PLA2G1B P04054 2/20 0.47
▸ ATG4B Q9Y4P1 2/20 0.47
▸ CES1 P23141 2/20 0.47
▸ KDM4E B2RXH2 1/20 0.47
▸ CES2 O00748 1/20 0.47
▸ TERT O14746 1/20 0.47
▸ NPC1 O15118 1/20 0.47
▸ PLIN1 O60240 1/20 0.47
▸ S1PR4 O95977 1/20 0.47
▸ LMNA P02545 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9672660 0.81 MEN1 (0.43) MEN1KMT2ACDC25BMAOATDP2
SCHEMBL29714477 0.80 MEN1 (0.50) MEN1KMT2ACDC25BMAOATDP2
SCHEMBL112133 0.80 MEN1 (0.50) MEN1KMT2ACDC25BMAOATDP2
SCHEMBL7921203 0.79 — —
SCHEMBL26128819 0.78 MEN1 (0.47) MEN1KMT2ACDC25BMAOATDP2
SCHEMBL30218501 0.78 MEN1 (0.47) MEN1KMT2ACDC25BMAOATDP2
SCHEMBL1569131 0.77 GSTP1 (0.48) MEN1KMT2APOLBMAPK1KDM4E
SCHEMBL10621855 0.75 HDAC4 (0.47) MEN1KMT2AMAPK1LMNAMAPT
SCHEMBL28194035 0.75 MEN1 (0.45) MEN1KMT2ACDC25BMAOATDP2
SCHEMBL1266199 0.75 ALDH1A1 (0.61) MEN1KMT2APOLBMAPK1CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 15586 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240238264-A1 INHIBITORS OF SARM1 NADASE ACTIVITY AND USES THEREOF DISARM THERAPEUTICS, INC. 2024-07-18 — — US claimed
US-20240240024-A1 PHOTOSENSITIVE RESIN COMPOSITION, PHOTOSENSITIVE RESIN LAYER USING THE SAME, AND COLOR FILTER SAMSUNG SDI CO., LTD. (KR) 2024-07-18 — — US claimed
US-12037324-B2 Biarylmethyl heterocycles BRISTOL-MYERS SQUIBB COMPANY (US) 2024-07-16 — — US claimed
EP-4395549-A1 COMPOSITIONS AND METHODS FOR TARGETED DEGRADATION OF PROTEINS IN A PLANT CELL Oerth Bio LLC (US) 2024-07-10 — — EP claimed
WO-2024145585-A1 COMPOUNDS AND METHODS FOR TREATING CANCER THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-07-04 — — WO claimed
CN-118184965-A Polyimide-based polymer, and preparation method and application thereof 华南师范大学 2024-06-14 — — CN claimed
WO-2024114776-A1 BICYCLIC ABASIC NUCLEIC ACID ANALOGS AND OLIGOMERIC COMPOUNDS PREPARED THEREFROM 上海舶望制药有限公司 2024-06-06 — — WO claimed
WO-2024118966-A1 GLUTARIMIDE-CONTAINING PAN-KRAS-MUTANT DEGRADER COMPOUNDS AND USES THEREOF TIGER BIOTHERAPEUTICS INC. (US) 2024-06-06 — — WO claimed
WO-2024118960-A1 GLUTARIMIDE-CONTAINING KRAS-MUTANT DEGRADER COMPOUNDS AND USES THEREOF TIGER BIOTHERAPEUTICS INC. (US) 2024-06-06 — — WO claimed
EP-4368621-A1 METHOD FOR PREPARING NITROGEN-CONTAINING POLYCYCLIC FUSED RING COMPOUND, AND INTERMEDIATE AND USE OF COMPOUND Applied Pharmaceutical Science, Inc. (CN) 2024-05-15 — — EP claimed
US-4283508-A Fragrant prevulcanization inhibitors MONSANTO COMPANY (US) 1981-08-11 — — US claimed
US-4245064-A Activated solid carrier and a method of its preparation CESKOSLOVENSKA AKADEMIE VED (CS) 1981-01-13 — — US claimed
US-4131733-A PIGMENTS HOECHST AKTIENGESELLSCHAFT (DE) 1978-12-26 — — US claimed
US-4052371-A AZO PIGMENT OR DYE HAVING A NAPHTHYL-QUINAZALONE COUPLING COMPONENT BASF AKTIENGESELLSCHAFT (DT) 1977-10-04 — — US claimed
US-4052377-A PIGMENTS BASF AKTIENGESELLSCHAFT (DT) 1977-10-04 — — US claimed
US-4042577-A POLYESTERS, POLYAMIDES, CELLULOSE ACETATES SANDOZ LTD. (CH) 1977-08-16 — — US claimed
US-4041036-A NAPHTHO(1',2':5,6)-PYRANO(2,3-D)PYRIMIDINE DYES HOECHST AKTIENGESELLSCHAFT (DT) 1977-08-09 — — US claimed
US-4012372-A MONOAZO DISPERSE DYES EASTMAN KODAK COMPANY (US) 1977-03-15 — — US claimed
US-4006155-A Method for preparation of phosphorus polysulfides MONSANTO COMPANY (US) 1977-02-01 — — US claimed
US-3954398-A Polyester fibers dyed with a disazo disperse dyestuff CIBA-GEIGY AG (CH) 1976-05-04 — — US claimed
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