Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | CDC25B | P30305 | 3/20 | 0.50 |
| ▸ | MAOA | P21397 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | S100A4 | P26447 | 3/20 | 0.47 |
| ▸ | APAF1 | O14727 | 2/20 | 0.47 |
| ▸ | TDP2 | O95551 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CES1 | P23141 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | BLM | P54132 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | TERT | O14746 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29714477 | 1.00 | MEN1 (0.50) | MEN1KMT2ACDC25BMAOAPOLB | |
| SCHEMBL30218501 | 0.97 | MEN1 (0.47) | MEN1KMT2ACDC25BMAOAPOLB | |
| SCHEMBL94097 | 0.83 | MEN1 (0.41) | MEN1KMT2ACDC25BMAOAPOLB | |
| SCHEMBL19888 | 0.80 | MEN1 (0.50) | MEN1KMT2ACDC25BMAOAPOLB | |
| SCHEMBL9000986 | 0.78 | KMT2A (0.41) | MEN1KMT2AAPAF1TDP2KDM4E | |
| SCHEMBL8134807 | 0.77 | GSTP1 (0.43) | MEN1KMT2APOLBMAPK1KDM4E | |
| SCHEMBL2996853 | 0.73 | MEN1 (0.43) | MEN1KMT2ACDC25BMAOAPOLB | |
| SCHEMBL332450 | 0.72 | MEN1 (0.36) | MEN1KMT2ACDC25BMAOAPOLB | |
| SCHEMBL2765740 | 0.72 | MEN1 (0.36) | MEN1KMT2ACDC25BMAOAPOLB | |
| SCHEMBL2026326 | 0.69 | MEN1 (0.39) | MEN1KMT2ACDC25BMAOAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 669 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12246068-B2 | Enzymatically activatable peptide-redox modulator conjugates and use thereof | BRANDEIS UNIVERSITY (US) | 2025-03-11 | — | — | US | claimed |
| US-20220267266-A1 | IMPROVED, COST EFFECTIVE PROCESS FOR SYNTHESIS OF VITAMIN D3 AND ITS ANALOGUE CALCIFEDIOL FROM ERGOSTEROL | FERMENTA BIOTECH LIMITED (IN) | 2022-08-25 | — | — | US | claimed |
| CN-110156696-B | Preparation method of 1, 4-dichlorophthalazine | 海门瑞一医药科技有限公司 | 2022-03-04 | — | — | CN | claimed |
| WO-2018129171-A1 | ENZYMATICALLY ACTIVATABLE PEPTIDE-REDOX MODULATOR CONJUGATES AND USE THEREOF | BRANDEIS UNIVERSITY (US) | 2018-07-12 | — | — | WO | claimed |
| US-20180153889-A1 | MODULATION OF CELL FATES AND ACTIVITIES BY PHTHALAZINEDIONES | BACH PHARMA, INC. | 2018-06-07 | — | — | US | claimed |
| US-9968602-B2 | Modulation of cell fates and activities by phthalazinediones | BACH PHARMA, INC. (US) | 2018-05-15 | — | — | US | claimed |
| EP-2061450-B1 | METHODS OF MODULATING CELL PROLIFERATION AND CYST FORMATION IN POLYCYSTIC KIDNEY AND LIVER DISEASES | MEDICAL COLLEGE WISCONSIN INC (US) | 2017-04-19 | — | — | EP | claimed |
| EP-2398325-B1 | PHTHALAZINEDIONE FOR TREATING INTESTINAL DISEASES AND INFLAMMATORY CONDITIONS RELATED TO HIV-AIDS | BACH PHARMA INC (US) | 2016-09-07 | — | — | EP | claimed |
| US-20160237039-A1 | PHARMACEUTICAL GRADE PHTHALAZINEDIONES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Occhiuti & Rohlicek LLP | 2016-08-18 | — | — | US | claimed |
| EP-1655301-B1 | CYCLIC BIOISOSTERS OF PURINE SYSTEM DERIVATIVES AND A PHARMACEUTICAL COMPOSITION BASED THEREON | ZHILOV VALERY KHAZHMURATOVICH (RU) | 2015-03-11 | — | — | EP | claimed |
| WO-1991013941-A1 | WATER-INSOLUBLE AZO DYES, THEIR MANUFACTURE AND USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-09-19 | — | — | WO | claimed |
| EP-0224086-B1 | SUBSTITUTED BENZYL ETHERS | BAYER AG (DE) | 1990-10-24 | — | — | EP | claimed |
| EP-0270206-A1 | Assays | UNILEVER PLC (GB) | 1988-06-08 | — | — | EP | claimed |
| WO-1988001744-A1 | ASSAYS | UNILEVER PLC (GB) | 1988-03-10 | — | — | WO | claimed |
| EP-0236997-A2 | Luminescence-immuno tests, method for stabilizing and quality-control of the same | Henning Berlin GmbH Chemie und Pharmawerk (DE) | 1987-09-16 | — | — | EP | claimed |
| EP-0070588-B1 | METHOD OF PREPARING 1-ALPHA-HYDROXYVITAMIN D AND 1-ALPHA-HYDROXY-PREVITAMIN D COMPOUNDS, AND ADDUCT OF A PREVITAMIN D OR TACHYSTEROL COMPOUND WITH A SUITABLE DIENOPHILE | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1986-05-07 | — | — | EP | claimed |
| US-4539153-A | Method of preparing 1 α-hydroxyvitamin D and 1 α-hydroxyprevitamin D compounds, and adducts of a previtamin D or tachysterol compound with a suitable dienophile | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1985-09-03 | — | — | US | claimed |
| EP-0116454-A2 | Enhanced luminescent or luminometric assay | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1984-08-22 | — | — | EP | claimed |
| EP-0070588-A1 | Method of preparing 1-alpha-hydroxyvitamin D and 1-alpha-hydroxy-previtamin D compounds, and adduct of a previtamin D or tachysterol compound with a suitable dienophile | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1983-01-26 | — | — | EP | claimed |
| US-4181530-A | ELECTRON ATTRACTING PHTHALIMIDE | FUJI PHOTO FILM CO., LTD. (JP) | 1980-01-01 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180153889-A1 | MODULATION OF CELL FATES AND ACTIVITIES BY PHTHALAZINEDIONES | NFE2L2, GPX4, TXNRD2 | MEN1 3256/4885KMT2A 2220/4885CDC25B 299/4885 |
| US-20220267266-A1 | IMPROVED, COST EFFECTIVE PROCESS FOR SYNTHESIS OF VITAMIN D3 AND ITS ANALOGUE CALCIFEDIOL FROM ERGOSTEROL | CYP2R1, CYP24A1, VDR | MEN1 466/4885KMT2A 4138/4885CDC25B 2371/4885 |
| US-12246068-B2 | Enzymatically activatable peptide-redox modulator conjugates and use thereof | GPX1, GPX4, ENPEP | MEN1 3935/4885KMT2A 4121/4885CDC25B 673/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.