Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.61 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.61 |
| ▸ | CES2 | O00748 | 1/20 | 0.61 |
| ▸ | BCHE | P06276 | 1/20 | 0.61 |
| ▸ | CES1 | P23141 | 1/20 | 0.61 |
| ▸ | TYMS | P04818 | 4/20 | 0.56 |
| ▸ | PARP1 | P09874 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | PABPC1 | P11940 | 3/20 | 0.52 |
| ▸ | CASP1 | P29466 | 2/20 | 0.52 |
| ▸ | CASP7 | P55210 | 2/20 | 0.52 |
| ▸ | DNMT1 | P26358 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.50 |
| ▸ | FEN1 | P39748 | 1/20 | 0.50 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1381178 | 0.84 | KDM4E (0.48) | ALDH1A1MCL1CES2BCHECES1 | |
| SCHEMBL8891852 | 0.80 | BRD1 (0.42) | ALDH1A1MCL1CES2BCHECES1 | |
| SCHEMBL10702898 | 0.80 | NPSR1 (0.60) | ALDH1A1MCL1CES2BCHECES1 | |
| Acenaphthoquinone SCHEMBL141538 | 0.76 | ALDH1A1 (1.00) | ALDH1A1MCL1CES2BCHECES1 | |
| SCHEMBL18803237 | 0.76 | ALDH1A1 (0.89) | ALDH1A1MCL1CES2BCHECES1 | |
| Acenaphthoquinone SCHEMBL2156555 | 0.76 | ALDH1A1 (1.00) | ALDH1A1MCL1CES2BCHECES1 | |
| Acenaphthoquinone SCHEMBL29586645 | 0.76 | ALDH1A1 (1.00) | ALDH1A1MCL1CES2BCHECES1 | |
| SCHEMBL4854374 | 0.75 | BCHE (0.32) | BCHECES1L3MBTL1POLB | |
| SCHEMBL19888 | 0.75 | MEN1 (0.50) | ALDH1A1CES2BCHECES1TSHR | |
| SCHEMBL9041143 | 0.75 | CES1 (0.43) | ALDH1A1MCL1CES2BCHECES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 348 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2307461-B1 | POLYMERS FUNCTIONALIZED WITH IMIDE COMPOUNDS CONTAINING A PROTECTED AMINO GROUP | BRIDGESTONE CORP (JP) | 2017-02-08 | — | — | EP | claimed |
| CN-102143980-B | Polymers functionalized with imide compounds containing protected amino group | BRIDGESTONE CORP | 2014-03-12 | — | — | CN | claimed |
| JP-2011526957-A | — | — | 2011-10-20 | — | — | JP | claimed |
| EP-1901775-B1 | KININ ANTAGONISTS FOR TREATING BLADDER DYSFUNCTION | JERINI AG (DE) | 2011-08-24 | — | — | EP | claimed |
| CN-102143980-A | Polymers functionalized with imide compounds containing a protected amino group | BRIDGESTONE CORP | 2011-08-03 | — | — | CN | claimed |
| EP-2307461-A1 | POLYMERS FUNCTIONALIZED WITH IMIDE COMPOUNDS CONTAINING A PROTECTED AMINO GROUP | Bridgestone Corporation (JP) | 2011-04-13 | — | — | EP | claimed |
| US-20100004414-A1 | POLYMERS FUNCTIONALIZED WITH IMIDE COMPOUNDS CONTAINING A PROTECTED AMINO GROUP | BRIDGESTONE CORPORATION (JP) | 2010-01-07 | — | — | US | claimed |
| WO-2010002849-A1 | POLYMERS FUNCTIONALIZED WITH IMIDE COMPOUNDS CONTAINING A PROTECTED AMINO GROUP | BRIDGESTONE CORPORATION (JP) | 2010-01-07 | — | — | WO | claimed |
| JP-4238334-B2 | — | — | 2009-03-18 | — | — | JP | claimed |
| US-20080221039-A1 | Kinin Antagonists For Treating Bladder Dysfunction | JERINI AG (DE) | 2008-09-11 | — | — | US | claimed |
| EP-0661058-A1 | Use of bradykinin antagonists for the treatment of viral diseases | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-07-05 | — | — | EP | claimed |
| EP-0623350-A1 | Use of Bradykinin-antagonists for the manufacture of a medicament for the prophylaxis and treatment of arteriosclerosis | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-11-09 | — | — | EP | claimed |
| WO-1994010990-A1 | INHIBITION OF TNF PRODUCTION | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1994-05-26 | — | — | WO | claimed |
| US-5304549-A | Control or prevention of degenerative joint diseases | HOFFMANN-LA ROCHE INC. (US) | 1994-04-19 | — | — | US | claimed |
| EP-0564972-A2 | Peptides with N-terminal modifications having bradykinin antagonistic activity | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-10-13 | — | — | EP | claimed |
| CN-1077202-A | The peptide compounds of N-end modification | HOECHST AG (DE) | 1993-10-13 | — | — | CN | claimed |
| EP-0497192-A2 | Amino acid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1992-08-05 | — | — | EP | claimed |
| US-4497953-A | HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1985-02-05 | — | — | US | claimed |
| EP-0042639-B1 | AZIDO, IMIDO, AMIDO AND AMINO DERIVATIVES OF MERCAPTOACYL PROLINES AND PIPECOLIC ACIDS HAVING HYPOTENSIVE ACTIVITY | E.R. Squibb & Sons, Inc. (US) | 1984-08-22 | — | — | EP | claimed |
| EP-0042639-A2 | Azido, imido, amido and amino derivatives of mercaptoacyl prolines and pipecolic acids having hypotensive activity | E.R. Squibb & Sons, Inc. (US) | 1981-12-30 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221039-A1 | Kinin Antagonists For Treating Bladder Dysfunction | BDKRB2, BDKRB1, F2R | ALDH1A1 2255/4885MCL1 4774/4885CES2 3855/4885 |
| US-20100004414-A1 | POLYMERS FUNCTIONALIZED WITH IMIDE COMPOUNDS CONTAINING A PROTECTED AMINO GROUP | PARG, PIN1, NPEPPS | ALDH1A1 4339/4885MCL1 2597/4885CES2 2565/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.